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School of Medicine

Success Stories

Postbaccalaureate Research Education Program (PREP) at the University of South Carolina has helped a number of students from underrepresented groups or from a disadvantaged background pursue their research dreams. Below are several recent student success stories. 

 

Courtney Callahan

Courtney Callahan

As an avid lover of science and all things health related, Courtney Callahan always knew from a young age that she wanted to work in the health field. It was while a junior at Winthrop University working with her zoologist professor that her interest in bacteria and viruses peaked.

Clorissa Washington Hughes

Clorissa Washington Hughes

Hughes' acceptance into the University of South Carolina PREP provided her with invaluable mentorship, academic and professional development. She recently received her Ph.D. from the Chemistry Department at the UofSC, and accepted a postdoctoral fellowship at Johns Hopkins University School of Medicine conducting brain physiology and disease research.

Pederson

Obiamaka Obianyo Pederson

Pederson developed an early passion for science from her father, an internal and emergency medicine physician, who shared with her the transformative powers of medicine. At West Chester University of Pennsylvania, she was introduced to biochemistry and quickly learned that biochemistry is the foundation that can “elucidate how our bodies function and provide the key to unlocking the cures for diseases that plague our society."

Terika Smith

Terika Smith

For as long as Smith can remember, science has always been a part of her career goals. She received her first microscope when she was 8 years old and has been fascinated with exploring the unseen and unknown ever since. Originally, she had planned to choose a career in the medical field; however, watching the hit television show CSI opened up the world of scientific investigation for her.

Kandy Velazquez

Kandy Velazquez

The daughter of two teachers, Velázquez developed a passion for learning early. From a young age she also knew she was interested in science, but she fell in love with research while studying at the University of Puerto Rico. “I love research because it can answer questions,” Velázquez says. “Any question that you have, you can answer with science.”

Yvon Woappi

Yvon Woappi

Woappi's curiosity in life science ignited during his youth in Cameroon. He would often go to local parks with his father to identify various insects and mollusks. This curiosity magnified after his family immigrated to Pennsylvania where he received passionate lessons from an ardent AP biology teacher.

 

Publications by PREP Scholars

University of South Carolina PREP Scholars have published more than 120 papers since the program began.

* Indicates publication derived from work as a USC PREP Scholar or as a graduate student at USC. Many USC PREP Scholars have published abstracts which are not listed here.

Clicking on Link will take you to the PubMed entry for the paper which will link to the full text.

Ringkamp M, Tal M, Hartke TV, Wooten M, McKelvy A, Turnquist BP, Guan Y, Meyer RA, Raja SN.  (2012) Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers. 

Plos One. 7 (7):e42105.  Link

 

AM Schlenz, CB McClellan, TR Mark, AD McKelvy, E Puffer, CW Roberts, SM Sweitzer, JC Schatz. (2012)   Sensitization to Acute Procedural Pain in Pediatric Sickle Cell Disease: Modulation by Painful Vaso-occlusive Episodes, Age, and Endothelin-1.

Journal of Pain 13 (7): 656-65. Link

 

CY Chung, AF Carteret, AD McKelvy, F Yang, TV Hartke, S He., X Dong, S Raja, Y Guan. (2012). Analgesic properties of loperamide differ following systemic and local administration to rats after L5 spinal nerve injury.

European Journal of Pain. 16 (7): 1021-32. Link

 

Yang F, Chung CY, Wacnik PW, Carteret AF, McKelvy AD, Meyer RA, Raja SN, Guan Y.  (2011) Electrical stimulation at distinct peripheral sites in spinal nerve injured rats leads to different afferent activation profiles.

Neuroscience Letters. 505 (1): 52-57. Link

 

* McKelvy, AD, and Sweitzer SM.  (2009) Decreased Opioid Analgesia in Weanling Rats Exposed to Endothelin-1 during Infancy. Neuroscience Letters. 466 (3): 144-148. Link

 

* McKelvy, AD, and Sweitzer, S.M. (2009). Endothelin-1 exposure on postnatal day 7 alters expression of the endothelin B receptor and behavioral sensitivity to endothelin-1 on postnatal day 11.

Neuroscience Letters 451 (1): 89-93.  Link

 

* McClellan CM, Schatz JC, Mark TRM, McKelvy AD, Puffer E, Roberts C, Sweitzer SM. (2009). Criterion and convergent validity for four measures of pediatric pain in sickle cell disease

Clinical Journal Pain 25 (2): 146-52.

* Nesbitt TL, Roberts A, Tan H, Junor L, Yost MJ, Potts JD, Dettman RW, Goodwin RL (2009).  Coronary endothelial proliferation and morphogenesis are regulated by a VEGF-mediated pathway.

Dev Dyn. 238 (2): 423-30 Link

Obianyo, O., Qi, Q., Du, Y., Fu, H., Shiyong, L., Ye, K.  (2017) Blockade of Asparagine Endopeptidase inhibits cancer metastasis. 

J Med Chem. 60 (17):7244-7255. Link

 

Obianyo, O., Ye, K. (2013) Novel small-molecule activators of the Trk family of receptor tyrosine kinases. 

Biochim. Biophys. Acta, 1834 (10), 2213-2218 Link

 

* Obianyo, O., Thompson, PR. (2012) Kinetic mechanism of Protein Arginine Methyltransferase 6. 

J Biol Chem, 287 (8), 6062-6071. Link

 

* Obianyo, O., Causey, C.P., Jones, J.E., Thompson, P.R. (2011) Activity-based protein profiling of Protein Arginine Methyltransferase 1. 

Chem Biol, 6(10), 1127-1135. Link

(This article was listed as one of the Top Ten Most Read Articles in 2011 ACS Chemical Biology)

 

* Bicker, K.L., Obianyo, O., Rust, H.L., Thompson, P.R. (2011) A combinatorial approach to characterize the substrate specificity of Protein Arginine Methyltransferase 1. 

Mol Biosyst, 7 (1), 48-51. Link

 

* Obianyo, O., Causey, C.P., Osborne, T.C., Jones, J.E., Lee, Y., Stallcup, M.R., Thompson, P.R. (2010) A chloroacetamidine-based inactivator of Protein Arginine Methyltransferase 1. 

Chembiochem, 11 (9), 1219-1223. Link

 

* Obianyo, O., Osborne, T.C., Thompson, P.R. (2008) Kinetic mechanism of Protein Arginine Methyltransferase 1.

Biochemistry, 47, 10420-10427.  Link

 

* Osborne, T.C., Obianyo, O., Zhang, X., Cheng, X., Thompson, P.R. (2007) Protein Arginine Methyltransferase 1: Positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis.

Biochemistry, 46, 13370-13381. (The first two authors contributed equally to this work) Link

 

Patents

* Osborne, T.C., Obianyo, O., Causey, C.P., Thompson, P.R.  Chloroacetamidine-based inhibitors and activity-based probes for the Protein Arginine Methyltransferases. United States Patent Application Number 20100151506

Fowlkes V, Clark J, Fix C, Law BA, Morales MO, Qiao X, Ako-Asare K, Goldsmith JG, Carver W, Murray DB, Goldsmith EC. (2013) Type II diabetes promotes a myofibroblast phenotype in cardiac fibroblasts.

Life Sci. 92 (11): 669-76. Link

 

Fowlkes V, Wilson CG, Carver W, Goldsmith EC. (2012). Mechanical loading promotes mast cell degranulation via RGD-integrin dependent pathways.

J Biomech. 46 (4): 788-95. Link

 

Law B, Fowlkes V, Goldsmith JG, Carver W, Goldsmith EC. (2012) Diabetes-induced alterations in the extracellular matrix and their impact on myocardial function.

Microsc Microanal.18 (1): 22-34. Review. Link

 

Wilson CG, Stone JW, Fowlkes V, Morales MO, Murphy CJ, Baxter SC, Goldsmith EC. (2011). Age-dependent expression of collagen receptors and deformation of type I collagen substrates by rat cardiac fibroblasts.

Microsc Microanal.17 (4): 555-62. Link

 

* Singh M, Fowlkes V, Handy I, Patel CV, Patel RC. (2009). Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis.

J Mol Biol. 2009 385 (2): 457-68. Link

 

* Mittelstadt M, Frump A, Khuu T, Fowlkes V, Handy I, Patel CV, Patel RC. (2008). Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR.

Nucleic Acids Res.36 (3): 998-1008. Link

*A Fox, K Fox, CT Callahan. (2011) Detection of Biological Agents for the Prevention of Bioterrorism: Mass spectrometry and tandem mass spectrometry for protein biomarker discovery and bacterial speciation. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer 1st edition, 37-45.

 

*CT Callahan, K Fox, A Fox. (2009) The small acid soluble proteins (SASP α and SASP β) of Bacillus weihenstephanensis and Bacillus mycoides group 2 are the most distinct among the Bacillus cereus group.

 Molecular and Cellular Probes 23, 291-297. Link

 

*CT Callahan, E Castanha, K Fox, A Fox. (2008). The Bacillus cereus containing sub-branch most closely related to Bacillus anthracis, has single amino acid substitutions in small acid-soluble proteins, while remaining sub-branches are more variable.

Molecular and Cellular Probes  22:  207-211. Link

 

CT Callahan , Wilson KM, Ely B.  (2016) Characterization of the Proteins Associated with Caulobacter crescentus Bacteriophage CbK Particles.

rr Microbiol. 72 (1): 75-80. Link

*Ragin, M  (2012) Effect of Linear Furanocoumarins on Cell Migration in Breast Cancer and Genetic Analyses of African American and European American Breast Cancer Patients in South Carolina. African American Professors Program - Monograph Series. 

 

*Ragin M. (2010) Polymorphisms in Certain Diabetes Mellitus II-Related Genes May Play a Role in Disparities for Certain Risk Factors in Breast Cancer Amongst Blacks and Whites. Call and Response 3 (1): 47-56.

Sougiannis AT,  Vanderveen BN,  Cranford. TL, Enos RT, Velazquez KT,  McDonald S,  Chatzistamou L,  Fan D, Murphy EA. (2020) Weight Cycling Creates an Obesogenic Memory in Adipose Tissue Which Exacerbates the Inflammatory Response to Obesity. https://doi.org/10.1096/fasebj.2020.34.s1.00521 Link

 

Velázquez KT, Enos RT, Bader JE, Sougiannis AT, Carson MS, Chatzistamou I, Carson JA, Nagarkatti PS, Nagarkatti M, Murphy EA. (2019). Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. 

World J Hepatol. 11 (8): 619-637 Link

Sougiannis AT, VanderVeen BN, Enos RT, Velazquez KT, Bader JE, Carson M, Chatzistamou I, Walla M, Pena MM, Kubinak JL, Nagarkatti M, Carson JA, Murphy EA. (2019)  Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.

Brain Behav Immun. 80: 44-55. doi: 10.1016/j.bbi.2019.02.020. Epub 2019 Feb 23. Link

 

Bader JE, Enos RT, Velázquez KT, Carson MS, Sougiannis AT, McGuinness OP, Robinson CM, Murphy EA (2019). Repeated clodronate-liposome treatment results in neutrophilia and is not effective in limiting obesity-linked metabolic impairments.

Am J Physiol Endocrinol Metab. 316 (3): E358-E372 Link

 

Cranford TL, Velázquez KT, Enos RT, Sougiannis AT, Bader JE, Carson MS, Bellone RR, Chatzistamou I, Nagarkatti M, Murphy EA. (2019) Effects of high fat diet-induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model.

Cancer Biol Ther. 20 (4): 487-496  Link

 

Mehrpouya-Bahrami P, Chitrala KN, Ganewatta MS, Tang C, Murphy EA, Enos RT, Velazquez KT, McCellan J, Nagarkatti M, Nagarkatti P. (2017).

Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity.

Sci Rep. 7 (1): 15645. Link

 

Bader JE, Enos RT, Velázquez KT, Carson MS, Nagarkatti M, Nagarkatti PS, Chatzistamou I, Davis JM, Carson JA, Robinson CM, Murphy EA  (2018)  Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer.

Am J Physiol Gastrointest Liver Physiol. 314 (1): G22-G31. Link

 

Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Sougiannis AT, Pritchett C, Fan D, Carson JA, Murphy EA. (2017) miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice.

Physiol Rep.  5 (18). e13412. doi: 10.14814/phy2.13412. Link

 

Cranford TL, Velázquez KT, Enos RT, Bader JE, Carson MS, Chatzistamou I, Nagarkatti M, Murphy EA.  (2017)  Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model.   Cancer Biol Ther. 18 (2): 85-93.  Link

 

Enos RT, Velázquez KT, Carson MS, McClellan JL, Nagarkatti P, Nagarkatti M, Davis JM, Murphy EA. (2016) A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice.

PLoS One.11 (12): e0167979. Link

 

Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Chatzistamou I, Singh UP, Nagarkatti PS, Nagarkatti M, Davis JM, Carson JA, Murphy EA.(2016) Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model.

Am J Physiol Gastrointest Liver Physiol. 311 (4): G699-G712. Link

 

Enos RT, Velázquez KT, McClellan JL, Cranford TL, Nagarkatti M, Nagarkatti PS, Davis JM, Murphy EA. (2016)  High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer.

Am J Physiol Gastrointest Liver Physiol. 310 (11): G906-19. Link

 

Velázquez KT, Enos RT, McClellan JL, Cranford TL, Chatzistamou I, Singh UP, Nagarkatti M, Nagarkatti PS, Fan D, Murphy EA (2016). MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer.

Am J Physiol Gastrointest Liver Physiol. 310 (6): G347-58. Link

 

Cranford TL, Enos RT, Velázquez KT, McClellan JL, Davis JM, Singh UP, Nagarkatti M, Nagarkatti PS, Robinson CM, Murphy EA.  (2016) Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain.

Int J Obes (Lond). 40 (5): 844-51. Link

 

Murphy EA, Velazquez KT, Herbert KM (2015) Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk.  

Curr Opin Clin Nutr Metab Care. 18 (5): 515-20 Link

 

Enos RT, Velázquez KT, McClellan JL, Cranford TL, Walla MD, Murphy EA. (2015)  Lowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model.   

Nutr Res. 2015 35 (5): 449-59  Link

 

Murphy EA, Enos RT, Velázquez KT.  (2015)  Influence of Exercise on Inflammation in Cancer: Direct Effect or Innocent Bystander? 

 Exerc Sport Sci Rev. 43 (3):134-42  Link

 

Velázquez KT, Enos RT, Narsale AA, Puppa MJ, Davis JM, Murphy EA, Carson JA. (2014)  Quercetin supplementation attenuates the progression of cancer cachexia in ApcMin/+ mice.

J Nutr. 144 (6):868-75  Link

 

Enos RT, Velázquez KT, Murphy EA. (2014) Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases J Nutr Biochem. 25 (6): 600-12. Link

 

Day ST, Enos RT, McClellan JL, Steiner JL, Velázquez KT, Murphy EA. (2013) Linking Inflammation to tumorigenesis in a Mouse Model of High-Fat-Diet-Enhance Colon Cancer. Cytokine  64 (1): 454-62  Link

 

Puppa MJ, White JP, Velázquez KT, Baltgalvis KA, Sato S. Baynes JW, Carson JA.  (2012). The effect of exercise on IL-6-induced cachexia in the Apc (Min/+) mouse.

J Cachexia Sarcopenia Muscle. 3 (2): 117-37 Link

 

* Velázquez KT, Mohammad HK, Sweitzer SM. (2007) Protein kinase C in pain: involvement of multiple isoforms.

Pharmacol Res. 55 (6): 578-89.  Review. Link

 

Rivera-Arce JC, Morales-Crespo L, Vargas-Pinto N, Velázquez KT, Jorge JC. (2006) Central effects of the anabolic steroid17!-methyltestosterone in female anxiety.

Pharmacology, Biochemistry and Behavior 84 (2): 275-81

 

Smith SN,  Paige C, Velazquez KT,  Smith TP, Raja  SN ,  Wilson  SP, Sweitzer  SM (2015)  Injury-specific Promoters Enhance Herpes Simplex Virus-Mediated Gene Therapy for Treating Neuropathic Pain in Rodents

J Pain 16 (3):283-90. doi: 10.1016/j.jpain.2014.12.007. Link

Sahoo PK, Lee SJ, Jaiswal PB, Alber S, Kar AN, Miller-Randolph S, Taylor EE, Smith T, Singh B, Ho TS, Urisman A, Chand S, Pena EA, Burlingame AL, Woolf CJ, Fainzilber M, English AW, Twiss JL.  (2018)  Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.   

Nat Commun.  9 (1): 3358.  doi: 10.1038/s41467-018-05647-x. Link

 

Gomes C, Lee SJ, Gardiner AS, Smith T, Sahoo PK, Patel P, Thames E, Rodriguez R, Taylor R, Yoo S, Heise T, Kar AN, Perrone-Bizzozero N, Twiss JL. (2017)    Axonal localization of neuritin/CPG15 mRNA is limited by competition for HuD binding.

J Cell Sci. 130 (21): 3650-3662. Link

 

Smith SN, Paige C, Velazquez KT, Smith TP, Raja SN, Wilson SP,

Sweitzer SM. (2015) Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents.

J Pain. 16 (3): 283-90.  Link

 

Smith TP, Schlenz AM, Schatz JC, Maitra R, Sweitzer SM. (2015)

Modulation of pain in pediatric sickle cell disease: understanding the balance between endothelin mediated vasoconstriction and apelin mediated vasodilation.

Blood Cells Mol Dis. 54 (2):155-9.  Link

*Smith TP, Smith SN, Sweitzer SM. (2014)

Endothelin-1 induced desensitization in primary afferent neurons.

Neurosci Lett. 582: 59-64  Link

 

*Smith TP, Haymond T, Smith SN, Sweitzer SM. (2014)

Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain.

J Pain Res.  7: 531-45  Link

 

Smith T, Beasley S, Smith S, Mark I, Sweitzer SM (2014) Endothelin-1-induced priming to capsaicin in young animals.

Neurosci Lett. 567: 15-8  Link

Smith SN, Paige C, Velazquez KT, Smith TP, Raja SN, Wilson SP, Sweitzer SM (2015) Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents. J Pain. 16 (3): 283-90.  Link

 

*Smith TP, Smith SN, Sweitzer SM. (2014)

Endothelin-1 induced desensitization in primary afferent neurons.

Neurosci Lett. 582: 59-64   Link

 

*Smith TP, Haymond T, Smith SN, Sweitzer SM. (2014)

Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain.

J Pain Res. 7: 531-45  Link

 

Smith T, Beasley S, Smith S, Mark I, Sweitzer SM Endothelin-1-induced priming to capsaicin in young animals.

Neurosci Lett. 2014 567:15-8   Link

*Vazquez M, Dunn CA., Walsh KBA (2012). Fluorescent Screening Assay for Identifying Modulators of GIRK Channels. J. Vis. Exp. (62), e3850   Link

Schmidt K, Bari B, Ralle M, Washington-Hughes C, Muchenditsi A, Maxey E, Lutsenko S. (2019).  Localization of the Locus Coeruleus in the Mouse Brain. 

J Vis Exp. 145.  10.3791/58652. doi: 10.3791/58652.  Link

 

Washington-Hughes CL, Ford GT, Jones AD, McRae K, Outten FW. (2019). Nickel exposure reduces enterobactin production in Escherichia coli.

Microbiologyopen.  8 (4):e00691 Link

 

* Fukuto M, Nguyen QL, Vasilyev O, Mank N, Washington-Hughes CL, Kuzmenko I, Checco A, Mao Y, Wang Q, Yang L. (2013). Crystallization, structural diversity and anisotropy effects in 2D arrays of icosahedral viruses.

Soft Matter (Royal Society of Chemistry) DOI: 10.1039/c3sm51853a  Link

 

* Washington-Hughes CL, Cheng Y, Duan X, Cai L, Lee LA, Wang Q. (2013). In vivo virus-based macrofluorogenic probes target azide-labeled surface glycans in MCF-7 breast cancer cells.

Mol Pharm. 10 (1): 43-50.  Link

Li F, Yuan CW, Xu S, Zu T, Woappi Y, Lee CAA, Abarzua P, Wells M, Ramsey MR, Frank NY, Wu X, Mandinova A, Frank MH, Lian CG, Murphy GF.  (2019) Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation.

J Invest Dermatol. pii: S0022-202X (19) 33467-0. Link

Woappi Y, Hosseinipour M, Creek KE, Pirisi L (2018).  Stem Cell Properties of Normal Human Keratinocytes Determine Transformation Responses to Human Papillomavirus 16 DNA.

J Virol. 92 (11). pii: e00331-18   Link

 

Woappi Y, Singh OV.  (2016)  Commensals and Foodborne Pathogens can Arbitrate Epithelial-carcinogenesis.  

Br Microbiol Res J. 15 (3). 10.9734 Link

 

Woappi YL, Jangiti R, Singh OV.  (2014) Synthetic immunosurveillance systems: nanodevices to monitor physiological events.  

Biosens Bioelectron.  61: 152-64  Link

 

Woappi Y, Gabani P. Singh OV. (2013) Emergence of Antibiotic-Producing Microorganisms in Residential Versus Recreational Microenvironments.

British Microbiology Research Journal 3 (3): 280-294.  Link

 

Woappi Y, Gabani P, Singh A, Singh OV. (2016)  Antibiotrophs: The complexity of antibiotic-subsisting and antibiotic-resistant microorganisms.

Crit Rev Microbiol. 42(1): 17-30.  Link

Getter T, Margalit R, Kahremany S, Levy L, Blum E, Khazanov N, Keshet-Levy NY, Tamir TY, Ben Major M, Lahav R, Zilber S, Senderowitz H, Bradfield P, Imhof BA, Alpert E, Gruzman A. (2019)  Novel inhibitors of leukocyte transendothelial migration.  

Bioorg Chem.  92: 103250.   Link

 

Bocanegra JL, Fujita BM, Melton NR, Cowan JM, Schinski EL, Tamir TY, Major MB, Quintero OA.   The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes.  

Cytoskeleton (Hoboken). 77(3-4):149-166. doi: 10.1002/cm.21560 Link

 

Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, Gileadi C, Gileadi O, Godoi PH, Kapadia N, Müller S, Santiago AS, Sorrell FJ, Wells CI, Fedorov O, Willson TM, Zuercher WJ, Major MB.  (2019)  WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.    

Cell Rep.  26 (1): 79-93.e8  Link

 

Gao Y, Kardos J, Yang Y, Tamir TY, Mutter-Rottmayer E, Weissman B, Major MB, Kim WY, Vaziri C.   The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells.

Sci Rep. 2018 8 (1): 15304  Link

 

Alapin JM, Dines M, Vassiliev M, Tamir T, Ram A, Locke C, Yu J, Lamprecht R (2018) Activation of EphB2 Forward Signaling Enhances Memory Consolidation.  

Cell Rep.  23 (7): 2014-2025  Link

Mulvaney KM, Matson JP, Siesser PF, Tamir TY, Goldfarb D, Jacobs TM, Cloer EW, Harrison JS, Vaziri C, Cook JG, Major MB. (2016)

Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.

J Biol Chem.  291(45): 23719-23733 Link

 

Anastas JN, Kulikauskas RM, Tamir T, Rizos H, Long GV, von Euw EM, Yang PT, Chen HW, Haydu L, Toroni RA, Lucero OM, Chien AJ, Moon RT (2014) WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.  

J Clin Invest.  124 (7): 2877-90   Link

 

Das D, Preet R, Mohapatra P, Satapathy SR, Siddharth S, Tamir T, Jain V, Bharatam PV, Wyatt MD, Kundu CN.  (2014)   5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway. 

DNA Repair (Amst).  24:15-25. Link

*Fowlkes, V., Clark, J., Fix, C., Law, BA., Morales, MO, Qiao, X., Ako-Asare, K., Goldsmith,JG., Carver, W., Murray, DB., and Goldsmith, EC.(2013). Type II diabetes promotes a myofibroblast phenotype in cardiac fibroblasts.

Life Sciences 92: 669-676.    Link

 

*Sisco PN, Wilson CG, Davin C, Clark JC, Grzincic EM, Ako-Asare K, Goldsmith EC. Murphy CJ (2014). Adsorption of Cellular Proteins to Polyelectrolyte-Functionalized Gold Nanorods: A Mechanism for Nanoparticle Regulation of Cell Phenotype. 

PLoS One. 2014. 9 (2): e86670. doi: 10.1371/journal.pone.0086670. eCollection 2014. Link

 

Morrow CS, Porter TJ, Xu N, Arndt ZP, Ako-Asare K, Heo HJ, Thompson EAN, Moore DL. (2020). Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit.

Cell Stem Cell. 26 (4): 558-568.e9. doi: 10.1016/j.stem.2020.01.018  Link

Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, Havton LA, Schiavo G, Giger RJ, Langley B, Twiss JL. (2019) Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition.

J Cell Biol. 218 (6): 1871-1890.  Link

 

Merianda TT, Coleman J, Kim HH, Kumar Sahoo P, Gomes C, Brito-Vargas P, Rauvala H, Blesch A, Yoo S, Twiss JL. (2015)  Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth.

J Neurosci. 35(14):5693-706Link

 

*Butler RK, Sharko AC, Oliver EM, Brito-Vargas P, Kaigler KF, Fadel JR, Wilson MA. (2011)  Activation of phenotypically-distinct neuronal subpopulations of the rat amygdala following exposure to predator odor.

Neuroscience.  175: 133-44 Link

 

*Parrilla-Carrero J, Figueroa O, Lugo A, García-Sosa R, Brito-Vargas P, Cruz B, Rivera M, Barreto-Estrada JL (2009) The anabolic steroids testosterone propionate and nandrolone, but not 17alpha-methyltestosterone, induce conditioned place preference in adult mice.   Drug Alcohol Depend. 100 (1-2): 122-7  Link

Li H, Vento PJ, Parrilla-Carrero J, Pullmann D, Chao YS, Eid M, Jhou TC. (2019). Three Rostromedial Tegmental Afferents Drive Triply Dissociable Aspects of Punishment Learning and Aversive Valence Encoding.

Neuron. 104 (5): 987-999.e4  Link

 

Parrilla-Carrero J, Buchta WC, Goswamee P, Culver O, McKendrick G, Harlan B, Moutal A, Penrod R, Lauer A, Ramakrishnan V, Khanna R, Kalivas P, Riegel AC. (2018)   Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.  

J Neurosci.  38 (17): 4212-4229.  Link

 

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Cushion MT, Ashbaugh A, Hendrix K, Linke MJ, Tisdale N, Sayson SG, Porollo A.  (2018)  Gene Expression of Pneumocystis murina after Treatment with Anidulafungin Results in Strong Signals for Sexual Reproduction, Cell Wall Integrity, and Cell Cycle Arrest, Indicating a Requirement for Ascus Formation for Proliferation.   

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Cameron RB, Gibbs WS, Miller SR, Dupre TV, Megyesi J, Beeson CC, Schnellmann RG. (2019) Proximal Tubule β 2-Adrenergic Receptor Mediates Formoterol-Induced Recovery of Mitochondrial and Renal Function after Ischemia-Reperfusion Injury. 

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Gibbs WS, Collier JB, Morris M, Beeson CC, Megyesi J, Schnellmann RG (2018). 5-HT1F receptor regulates mitochondrial homeostasis and its loss potentiates acute kidney injury and impairs renal recovery.   

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Gibbs WS, Garrett SM, Beeson CC, Schnellmann RG. (2018)

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Gibbs WS, Weber RA, Schnellmann RG, Adkins DL. (2016)  Disrupted mitochondrial genes and inflammation following stroke.

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Curr Microbiol.  74 (7): 779-786.  Link

 

Atanelishvili I, Shirai Y, Akter T, Noguchi A, Ash KT, Misra S, Ghatak S, Silver RM, Bogatkevich GS. (2016)  D1398G Variant of MET Is Associated with Impaired Signaling of Hepatocyte Growth Factor in Alveolar Epithelial Cells and Lung Fibroblasts.

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Renrick AN, Dunbar ZT, Shanker A (2019) Update on the current revolution in cancer immunotherapy

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Tafreshi NK, Tichacek CJ, Pandya DN, Doligalski ML, Budzevich MM, Kil H, Bhatt NB, Kock ND, Messina JL, Ruiz EE, Delva NC, Weaver A, Gibbons WR, Boulware DC, Khushalani NI, El-Haddad G, Triozzi PL, Moros EG, McLaughlin ML6 Wadas TJ, Morse DL. (2019)

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Gunaratne GS, Yahya NA, Dosa P, Marchant JS (2018).  Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers.

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*Scott DC, Scott L, Wilson K, Ross K, Ingram D, Lewter T, Herring J, Linton L, Duncan D, Aikins A, Ely B.  (2018)  Complete Genome Sequence of a Wild-Type Isolate of Caulobacter vibrioides Strain CB2.

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*Scott DC, Wilson K, Ross K, Ingram D, Lewter T, Herring J, Duncan D, Aikins A, Ely B  (2018)  Complete Genome Sequence of a Wild-Type Isolate of Caulobacter vibrioides Strain CB1.   

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Callahan CT, Wilson KM, Ely B. (2016)   Characterization of the Proteins Associated with Caulobacter crescentus Bacteriophage CbK Particles.

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Becker W, Alrafas H, Wilson K, Cai G, Miranda K, Culpepper C, Chatzistmou I, Nagarkatti P, and Nagarkatti M. (2020) Cannabinoid receptor activation protects against colitis and associated colon cancer through hematopoietic and non-hematopoietic means

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Mohammed A, Algheeta H, Wilson K, Miranda K, Chatzistmou I, Cai G, Nagarkatti P, and Nagarkatti M. (2020)  Effect of cannabinoid treatment on immune cell functions during acute lung injury

IN PREPARATION

Harmon KA, Lane BA, Boone RE, Afshari A, Berdel HO, Yost MJ, Goodwin RL, Friedman HI, Eberth JF (2018) Therapeutic Engineered Hydrogel Coatings Attenuate the Foreign Body Response in Submuscular Implants.

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Jones RS, Chang PH, Perahia T, Harmon KA, Junor L, Yost MJ, Fan D, Eberth JF, Goodwin RL (2017) Design and Fabrication of a Three-Dimensional In Vitro System for Modeling Vascular Stenosis.   

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Liao CP, Tchegnon E, Le LQ.   (2019) Double-Stranded RNA Sensing Determines Epithelial Cell Identity.  

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Liao CP, Booker RC, Brosseau JP, Chen Z, Mo J, Tchegnon E, Wang Y, Clapp DW, Le LQ.  (2018)  Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis.    

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Alexander T. Sougiannis, Brandon N. Vanderveen, Taryn L. Cranford,  Reilly T. Enos,  Kandy T. Velazquez,  Sierra McDonald, Loulia Chatzistamou.  Daping Fan.  E. Angela Murphy. (2020) Weight Cycling Creates an Obesogenic Memory in Adipose Tissue Which Exacerbates the Inflammatory Response to Obesity.

FASEB J .https://doi.org/10.1096/fasebj.2020.34.s1.00521

Rodriguez M and Pena, M. (2020) Regulation of Stress Induced Hematopoiesis.

Current Opinion in Hematology. July 2020

Chavez B, Farmaki E, Zhang Y, Altomare D, Hao J, Soltnamohammadi E, Shtutman M, Chatzistamou I, and Kiaris H. (2020) A strategy for the Identification of Paracrine Regulators of Cancer Cell Migration.

Clinical and Experimental Pharmacology and Physiology In press


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