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School of Medicine Columbia

Faculty and Staff

Ioulia Chatzistamou

Title: Clinical Associate Professor of Pathology, Microbiology & Immunology
Department: Pathology, Microbiology & Immunology
School of Medicine Columbia
Phone: 803-216-3467

Pathology, Microbiology & Immunology
Basic Science Bldg 1, Room B-32



  • Research Fellow in Pathology, Massachusetts General Hospital, Boston, MA, USA
  • Research Instructor, Tulane University Medical School, Dept. of Medicine, Section of Experimental Medicine and Research Associate at the VA Medical Center, Endocrine, Polypeptide and Cancer Institute, New Orleans, LA, U.S.A
  • Residency in Anatomic Pathology, Aretaieion University Hospital, Athens, Greece
  • Ph.D., Medical School, University of Athens, Greece
  • M.D., Medical School, University of Athens, Greece
  • B.S., Dept. of Biology, University of Athens, Greece


My research focuses in the identification and characterization of molecular alterations associated with carcinogenesis. I am also interested in the characterization of the pathologic changes that occur in the neoplastic stroma and how the deregulation of the microenvironment promotes cancer growth and influences tumors’ histopathology. Besides cancer, I also study the histopathological characterization of tissues from animal models of human diseases with a particular focus on the ER stress – associated pathologies such as diabetes.


  • Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H. Modulation of Pancreatic Islets' Function and Survival During Aging Involves the Differential Regulation of Endoplasmic Reticulum Stress by p21 and CHOP. Antioxid Redox Signal. 27(4):185-200, 2017
  • Farmaki E, Kaza V, Papavassiliou AG, Chatzistamou I, Kiaris H. Induction of the MCP chemokine cluster cascade in the periphery by cancer cell-derived Ccl3. Cancer Lett. 389:49-58. doi: 10.1016/j.canlet.2016.12.028, 2017
  • Cranford TL, Velázquez KT, Enos RT, Bader JE, Carson MS, Chatzistamou I, Nagarkatti M, Murphy EA Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model. Cancer Biol Ther. 18(2):85-93. doi: 10.1080/15384047.2016.1276135, 2017
  • Fanourakis G, Tosios K, Papanikolaou N, Chatzistamou I, Xydous M, Tseleni-Balafouta S, Sklavounou A, Voutsinas GE, Vastardis H. Evidence for APOBEC3B mRNA and protein expression in oral squamous cell carcinomas. Exp Mol Pathol. 101(3):314-319. doi: 10.1016/j.yexmp.2016.11.001, 2016
  • Kim J, Vaish V, Feng M, Field K, Chatzistamou I, Shim M. Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice. Aging (Albany NY). 8(10):2392-2406. doi: 10.18632/aging.101060, 2016
  • Mihailidou C, Katsoulas N, Panagiotou E, Farmaki E, Sklavounou A, Kiaris H, Chatzistamou I. Endoplasmic Reticulum stress is associated with the pathogenesis of Pemphigus Vulgaris. Experimental Dermatology. 25(9):731-3. 2016 Featured on the cover of the September issue of ED
  • Velázquez KT, Enos RT, McClellan JL, Cranford TL, Chatzistamou I, Singh UP, Nagarkatti M, Nagarkatti PS, Fan D, Murphy EA. MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 310(6): G347-58, 2016
  • Velazquez KT, Enos RT, Carson MS, Cranford TL, Bader J, Chatzistamou I, Singh U, Nagarkatti PS, Nagarkatti M, Davis JM, Carson JA, Murphy EA. Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model. Am J Physiol Gastrointest Liver Physiol 311(4):G699-G712, 2016
  • Farmaki E, Chatzistamou I, Kaza V & Kiaris H. A Ccl8 gradient drives breast cancer cell dissemination. Oncogene. 35(49):6309-6318, 2016
  • Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H. Improvement of chemotherapeutic drug efficacy by endoplasmic reticulum stress. Endocr Relat Cancer. 22(2):229-38. 2015 (Commentary appeared in Endocr Relat Cancer. 2015 Mar 19. pii: ERC-15-010)
  • Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H. Regulation of p21 during diabetes-associated stress of the endoplasmic reticulum. Endocr Relat Cancer. 22(2):217-28, 2015. (Commentary appeared in Endocr Relat Cancer. 2015 Mar 19. pii: ERC-15-010) Featured on the cover of the Dec. issue of ERC

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