Education

B.A., 2015, Bard College

Ph.D., 2019, University of Texas at Austin

Honors and Awards

ACS Irving S. Sigal Postdoctoral Fellowship, 2020-2022; Ereztech Bridge Forward Award, 2020; ACS Analytical Chemistry Graduate Student Fellowship, 2018-2019; Henze Teaching Award, 2018.

Research Interests

Our research group investigates important questions at the interface of chemistry, biology, and medical research, employing a combination of analytical chemistry, electrochemical methods, spectroscopic imaging, as well as experimental approaches in microbiology. In particular, the monitoring of the metabolic dynamics of clinically relevant bacteria, virulence mechanisms, and biomarkers related to human health is not only a fundamental scientific problem but also a challenge of vast importance, especially in tailoring effective diagnostic and treatment strategies. Our goal is to establish and perfect electrochemical platforms for the quantitative study of mechanisms and processes for advancing the science and technology of human health.

Selected Publications

Weber, C. J.†; Whisonant, M. D.† (†authors contributed equally); Clay, O. M., and Simoska, O. "Surface-display Techniques in the Design of Electrochemical Biosensors for Health Monitoring " ECS Sensors Plus 2024, 3, 020603. DOI: 10.1149/2754-2726/ad49af.

Weber, C. J.; Clay, O. M.; Lycan, R. E.; Anderson, G. K.; and Simoska, O. "Advances in Electrochemical Biosensor Design for the Detection of the Stress Biomarker Cortisol" Analytical and Bioanalytical Chemistry 2023, 416, 87. DOI: 10.1007/s00216-023-05047-1.
 
Simoska, O.; Cummings Jr., D. A.; Gaffney, E. M.; Langue, C.⊥; Primo, T. G.⊥; Weber, C. J.; Witt, C. E.;   Minteer, S. D. “Enhancing the Performance of Microbial Electrochemical Systems via Metabolic Engineering of Escherichia coli” ACS Sustainable Chemistry and Engineering 2023, 11, 11855. DOI: 10.1021/acssuschemeng.3c01593. 
 
Boucher, D. G.; Carroll, E.; Nguyen, Z.; Jadhav, R. G.; Simoska, O.; Beaver, K.; Minteer, S. D. “Bioelectrocatalytic Synthesis: Concepts and Applications” Angewandte Chemie 2023, 63, e202307780. DOI: 10.1002/anie.202307780. 
 
Simoska, O.; Rhodes, Z.; Carroll, E.; Petrosky, K. N.; Minteer, S. D. “Biological Anolyte Regeneration System for Redox Flow Batteries” ChemComm 2023, 59, 2142. DOI: 10.1039/D2CC06011F. 
 
Simoska, O.; Minteer, S. D. “Techniques in Electroanalytical Chemistry” American Chemical Society, 2022. DOI: 10.1021/acsinfocus.7e5021. 
 
Rhodes, Z.†; Simoska, O.†,* (†authors contributed equally); Dantanarayana, A.; Stevenson, K. J.; Minteer, S. D.* “Using Structure-Property Relationships to Understand the Mechanism of Mediated Extracellular Electron Transfer in Escherichia coli” iScience 2021, 24, 103033. (*co-corresponding authors). DOI: 10.1016/j.isci.2021.103033. 
 
Simoska, O.; Gaffney, E. M.; Lim, K.; Beaver, K.; Minteer, S. D. “Understanding the Properties of Phenazines that Promote Extracellular Electron Transfer in Escherichia coli” Journal of the Electrochemical Society 2021, 168, 025503. DOI: 10.1149/1945-7111/abe52d. 
 
Simoska, O.; Duay, J.; Stevenson K. J. “Electrochemical Detection of Multianalyte Biomarkers in Wound Healing Efficacy” ACS Sensors 2020, 5, 3557. DOI: 10.1021/acssensors.0c01697.
 
Chen, H.†; Simoska, O.† (†authors contributed equally); Lim, K.; Grattieri, M.; Yuan, M.; Dong, F.; Lee, Y. S.; Beaver, K.; Weliwatte, S.; Gaffney, E. M.; Minteer, S. D. “Fundamentals, Applications, and Future Directions of Bioelectrocatalysis” Chemical Reviews 2020, 120, 12903. ACS Editor’s Choice. DOI: 10.1021/acs.chemrev.0c00472. 
 
Simoska, O.; Stevenson K. J. “Electrochemical Sensors for Rapid Detection of Pathogens in Real-Time” (invited contribution to the themed collection on versatile electrochemical approaches). Analyst 2019, 144, 6461. DOI: 10.1039/c9an01747j. 
 
Simoska, O.; Sans, M.; Eberlin, L. S.; Shear, J. B.; Stevenson K. J. “Electrochemical Monitoring of the Impact of Polymicrobial Infections on Pseudomonas aeruginosa and Growth Dependent Medium” Biosensors and Bioelectronics 2019, 142, 111538. DOI: 10.1016/j.bios.2019.111538.
 
Simoska, O.; Sans, M.; Fitzpatrick, M. D.; Crittenden, C. M.; Eberlin, L. S.; Shear, J. B.; Stevenson K. J. “Real-time Electrochemical Detection of Pseudomonas aeruginosa Phenazine Metabolites using Transparent Carbon Ultramicroelectrode Arrays” ACS Sensors 2019, 4, 170. DOI: 10.1021/acssensors.8b01152. 
 
Darch, S.; Simoska, O.; Fitzpatrick, M. D.; Barraza, J. P.; Stevenson K. J.; Bonnecaze, R. T.; Shear, J. B.; Whiteley, M. “Biological Determinants of Quorum Signaling in P. aeruginosa Infection Model” Proceeding of the National Academy of Sciences of the USA 2018, 115, 4779. DOI: 10.1073/pnas.1719317115.