Biochemistry and Molecular Biology
The research interests of these faculty encompass all areas of biochemistry, including
cell and molecular biology, enzymology, spectroscopy, protein crystallography, and
"We focus on the structural analysis of food and inhaled allergens to determine the
molecular basis of allergic diseases. Moreover, we study proteins that are potential
targets for the development of antibiotics and pesticides."
"Development of electrochemical microelectrode methodology for real-time quantitate
analysis of biologically and environmentally important molecules. Neurotransmitter
roles in depression and neurodegeneration. Real-time trace metal speciation studies."
"We focus on defining the mechanisms by which growth factors transduce their signals
in cells to alter cellular behavior using a combination of biochemical, cell signaling,
and cell biological approaches. Our goal is to identify mechanisms that may serve
as therapeutic targets for the treatment of human disease."
"Our research is focused on mining microbial genomes to discover drug leads, biosynthetic
pathways, and new enzyme biocatalysts. We employ an interdisciplinary approach combining
organic chemistry, natural products chemistry, biochemical analysis, metabolomics,
genetic engineering, and synthetic biology."
"We are developing methods to leverage enzyme catalysts for the production of novel
therapeutics and sustainable fuels."
“We are interested in understanding how cells regulate the essential metal iron and
control thiol-disulfide balance using yeast as a model system. We employ a multidisciplinary
approach that includes protein biochemistry, biophysical spectroscopy, molecular genetics,
and cell biology."
"We study the homeostasis and metabolism of essential metals like copper, iron and
zinc, with the goals of disrupting metal metabolism in bacteria during infection and
correcting defects in human metal metabolism that lead to disease."
"Our focus is on understanding how human serum complement proteins C5b, C6, C7, C8
and C9 assemble to form a lethal, pore-like 'membrane attack complex' (MAC) on the
membrane of infectious organisms."
"We use state-of-the-art single-molecule spectroscopic techniques to resolve the conformational
dynamics of complicated biomolecules."
"The overall research objective of Dr. Qian Wang's laboratory focuses on using chemical
biology tools to probe intracellular activities and the development of hierarchically-structured
nanomaterials to study the cooperative response of cells to extracellular matrixes."