Education

B.S., 2004, Moscow State University
M.S., 2004, Moscow State University
Ph.D., 2011, Colorado State University

Honors and Awards

Breakthrough Star Award, 2018; National Science Foundation CAREER Award, 2017; Doctoral New Investigator Award, ACS PRF, 2014

Research Interests

Research areas: Inorganic chemistry and catalysis, organometallics, metal-free bond activation.

Research in the group involves the synthesis of molecular catalysts for activation of important substrates such as dihydrogen, carbon dioxide, and unsaturated organic compounds. Students with interest in catalysis, inorganic, and organometallic chemistry are encouraged to join. Group members will receive a rigorous training in inorganic and organometallic chemistry, catalysis, air-free synthetic methods, and spectroscopic methods. 
 
Metal-free Bond Activation by Redox-Active Main-Group Systems
We have harnessed redox-activity of carborane clusters for the cage-driven activation of strong bonds at the exohedral reaction centers. We designed a new metal-free molecular framework containing clusters with two critical features typically associated with transition metals: binding sites and the ability to cycle through two-electron redox states. 
 
Catalysis with Transition Metal Complexes Supported by Carboranyl-Based Ligands
Transition metal complexes with new unusual bonding and reactivity patterns in catalysis are pursued. We use three-dimensional carborane clusters as a chemically versatile platform for stabilization of reactive transition metal complexes designed for small molecule activation and group transfer. 
 
Pre-Organized Lewis Pairs for Small Molecule Activation
We work on new modes of activation of organic substrates by a cooperative action of high-valent transition metal complexes and sterically hindered bases. Our recent findings include the novel activation of nitriles with direct formation of zwitterionic vinylimido complexes. The scope of the reaction includes a range of substituted unactivated nitriles. 

Publications

Nussbaum, B. C.; Humphries, A. L.; Gange, G. B.; Peryshkov, D. V. Redox-active Carborane Clusters in Bond Activation Chemistry and Ligand Design. Chemical Communications 2023 DOI: 10.1039/D3CC03011C
 
Gange, G. B.; Humphries, A. L.; Royzman, D. E.; Smith, M. D.; Peryshkov, D. V. Metal-Free Bond Activation by Carboranyl Diphosphines. Journal of the American Chemical Society 2021 DOI: 10.1021/jacs.1c05387
 
Jayaweera, H. D. A. C.; Rahman, M. M.; Pellechia, P. J.; Smith, M. D.; Peryshkov, D. V. Free Three-Dimensional Carborane Carbanions. Chemical Science 2021 DOI: 10.1039/D1SC02252K
 
Eleazer, B. J.; Smith, M. D.; Popov, A. A.; Peryshkov, D. V. Expansion of the (BB)>Ru Metallacycle with Coinage Metal Cations: Formation of B-M-Ru-B (M = Cu, Ag, Au) Dimetalacyclodiboryls Chemical Science 2018 DOI: 10.1039/C8SC00190A 
 
Eleazer, B. J.; Smith, M. D.; Popov, A. A.; Peryshkov, D. V. (BB)-Carboryne Complex of Ruthenium: Synthesis by Double B–H Activation at a Single Metal Center Journal of the American Chemical Society 2016 DOI: 10.1021/jacs.6b05172