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Department of Biological Sciences

Faculty and Staff Directory

Lydia Matesic

Title: Associate Professor
Research Concentration - Developmental Biology
Department: Biological Sciences
College of Arts and Sciences
Phone: 803-777-2520
Office: CLS, Room 703
Lydia Matesic Profile Picture


J. P. White, J. W. Baynes, S. L. Welle, M. C. Kostek, L. E. Matesic, S. Sato, and J. A. Carson. 2011. The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the ApcMin/+ mouse. PLoS One. 6: e24650. [PDF]

L. J. Hofseth and L. E. Matesic. 2011. An apple a day keeps colitis away. The Journal of Leukocyte Biology. 90: 1037-1038.

L. Zhao, J. Huang, H. Zhang, Y. Wang, L. E. Matesic, M. Takahata, H. Awad, D. Chen, and L. Xing. 2011. Tumor necrosis factor Inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 Ligase Wwp1. Stem Cells. 29: 1601-1610. [PDF]

C. Rathinam, L. E. Matesic, and R. A. Flavell. 2011. The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells. Nature Immunology. 12: 399-407. [PDF]

A. A. Chumanevich, C. P. Causey, B. A. Knuckley, J. E. Jones, D. Poudyal, A. P. Chumanevich, T. Davis, L. E. Matesic, P. R. Thompson, and L. J. Hofseth. 2011. Suppression of colitis in mice by Cl-Amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology: Gastrointestinal and Liver Physiology. 300: G929-938. [PDF]

Y. Jin, A. B. Hofseth, X. Cui, A. J. Windust, A. A. Chumanevich, L. E. Matesic, N. P. Singh, M. Nagarkatti, P. S. Nagarkatti, and L. J. Hofseth. 2010. American Ginseng Suppresses Colitis through p53-Mediated Apoptosis of Inflammatory Cells. Cancer Prevention Research. 3: 339-347. [PDF]

M. Tao, P. C. Scacheri, J. M. Marinis, E. W. Harhaj, L. E. Matesic, and D. W. Abbott. 2009. ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to Influence Inflammatory Signaling Pathways. Current Biology. 19: 1255-1263. [PDF]

Y. Jin, V. S. Kotakadi, L. Ying, A. B. Hofseth, X. Cui, P. A. Wood, A. Windust, L. E. Matesic, E. Pena, C. Chiuzan, N. P. Singh, M. Nagarkatti, P. S. Nagarkatti, M .J. Wargovich, and L. J. Hofseth. 2008. American ginseng suppresses inflammation and DNA damage associated with mouse colitis. Carcinogenesis. 29: 2351-2359.

L. E. Matesic, N. G. Copeland, and N. A. Jenkins. 2008. Itchy mice: the identification of a new pathway for the development of autoimmunity. Current Topics in Microbiology and Immunology. 321: 185-200.

V. S. Kotakadi, Y. Jin, A. B. Hofseth, L. Ying, X. Cui, S. Volate, A. Chumanevich, P. A. Wood, R. L. Price, A. McNeal, U. P. Singh, N. P. Singh, M. Nagarkatti, P. S. Nagarkatti, L. E. Matesic, K. Auclair, M. J. Wargovich, and L. J. Hofseth. 2008. Ginkgo biloba extract EGb761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis. Carcinogenesis. 29: 1799-1806.

N. Shembade, N. S. Harhaj, K. Parvatiyar, N. G. Copeland, N. A. Jenkins, L. E. Matesic, and E. W. Harhaj. 2008. The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20. Nature Immunology. 9: 254-262. [PDF]

C. Chen and L. E. Matesic. 2007. The Nedd4-like family of E3 ubiquitin ligases and cancer. Cancer and Metastasis Reviews. 3-4: 587-604. [PDF]

L. E. Matesic, D.C. Haines, N. G. Copeland, and N. A. Jenkins. 2006. Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Human Molecular Genetics. 15: 3485-3497.

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