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Center for Clinical and Translational Research

P&D Project Program

The Pilot and Developmental (P&D) Research Program provides competitive funding to advance innovative clinical and translational research. 

P&D Program Overview

The P&D Project Program provides competitive funding to support one-year Pilot Projects (up to $100,000) and one- or two-year Developmental Projects (up to $200,000 total). The program requires a pre-application and full proposal process and includes a rigorous scientific review. Eligible faculty across South Carolina institutions may apply, with required participation of a USC PI or co-investigator and a clinical collaborator affiliated with a qualifying Midlands clinical facility. Projects are expected to generate strong preliminary data, demonstrate meaningful use of ClinTrUSC cores, and position investigators to submit competitive extramural grant applications. 

Notice of Funding Opportunity

View the NOFO [PDF]

 

The P&D Program Cycle III funding opportunity application is now open.   
Pre-applications are required and due by June 22, 2026
Full applications are due by August 3, 2026
For questions, please contact the HR core @ clintruscHRcore@uscmed.sc.edu  

 




P&D Funded Projects

Cycle I

Norma Frizzell, Ph.D.

Investigating the relationship between circulating cysteine adducts and diabetes complications

Elizabeth Regan, DPT, Ph.D.

Train Your Brain Fitness SC: An exercise intervention for people with cognitive impairments

Michael D. Wyatt, Ph.D.

Targeted Therapeutics with a focus on Pediatric Oncology

Peisheng Xu, Ph.D.

The combination of PD-L1 and CTLA-4 Nano-ERASERs for TNBC therapy

Chih-Hsiang (Jason) Yang, Ph.D

The Impact of Mindful Walking on Neural Correlates of Executive Function in SC Older Adults at Risk of Alzheimer's and Dementias


P&D Funded Projects

Cycle II

Daping Fan

Targeting Mixed Alzheimer’s Disease and Vascular Dementia

Claudia Grillo

Ginsenosides as a new therapy for obesity and its co-morbidities

Melissa Nolan

Advancing Tick-Borne Disease Diagnostics

Christopher Rorden

SOOP+: A Multimodal Imaging Resource for AI-Driven Stroke Outcome Prediction



Center for Clinical and Translational Research


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