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School of Medicine Greenville

Student Research

Student Research Project Database (Summer 2021 Research Projects)

Medical students engage in research across the Prisma Health Sciences Center (UofSC SOMG, Prisma CLE, Clemson, Furman, UofSC Arnold School of Public Health). These research experiences include but are not limited to:
  • Clinical Research
  • Translational Research (including bench research in cell, molecular biology, biochemistry, microbiology and immunology)
  • Community Health
  • Medical Education
  • Population Health/Health Policy
The database below includes a listing of research projects that rising M2 students participated in during the summer of 2021. Additional information regarding student projects is available upon request.

Project Title Mentor Name Department Research Keywords
(hidden column)
CenteringPregnancy – Depression Diagnosis Among Prenatal Women Amy Crockett OBGYN CenteringPregnancy, Group Prenatal Care, Depression
CenteringPregnancy - Prenatal Quality Care Measures Amy Crockett OBGYN CenteringPregnancy, Group Prenatal Care, Depression, prenatal quality care, HIV, GBS, GDM, Tdap, Flu
Prenatal Quality Care Measures by Race Amy Crockett OBGYN Prenatal Quality Care, HIV, GBS, GDM, Tdap, Flu, race/ethnicity, disparities
Mechanisms of SARS-CoV-1 Non-Structural Protein-1 (Nsp-1)-mediated Immune Regulation Dr. Jennifer Grier Biomedical Sciences Immune evasion by severe acute respiratory syndrome-associated coronavirus (SARS-CoV) using non-structural protein 1 (nsp1) has been a topic of interest since the 2003 epidemic. It has been suggested that nsp1 is responsible for a delayed and disorganized activation of the immune system leading to worse clinical outcomes. Nsp1’s known functions include antagonizing antiviral pathways that would otherwise limit viral replication and blocking eukaryotic translation crucial for host defense. During viral infection, nsp1 localizes in cells to boundaryless aggregates of cell machinery called stress granules. Interestingly, in stress granules, nsp1 may interact with ADAR1, a regulator of retinoic acid inducible gene I (RIG-I)-like receptors (RLRs), which specialize in detecting viral infections. Our lab created mutated versions of nsp1 lacking one or both nsp1 functions or enhanced antiviral activity using site-directed mutagenesis and confirmed our mutants using sanger sequencing. Using fluorescent microscopy, we hope to visualize the effect of distinct nsp1 functions on ADAR cellular localization in human epithelial lung cells. We will assess potential downstream effects via qRT-PCR on RLR-inducible genes and inflammatory cytokines associated with the antiviral response. The results from this study will provide a better understanding of nsp1 function and hopefully provide therapeutic targets to support detection and clearance of SARS-CoV infection by the immune response.
The Impact of Posaconazole on Aspergillus Fumigatus Growth in Larval Zebrafish Emily Rosowski, PhD Clemson Research Aspergillus Fumigatus, macrophages, Posaconazole, zebrafish
SpyGlass Christine Schammel Pathology Comparing the efficacy of biliary brushings to that of SpyGlass-directed biopsies in the evaluation of biliary strictures.
Empathy Behind the Scenes: Training future healthcare providers to treat opioid use disorder with a focus on patient narrative through forum theatre Margie Stevens Addiction Research Center Medical Education, Medical Students, Theatre Arts, Art Education, Audience Participation, Improvisation, Forum Theatre, Ethics, Simulation, Communication Skills
Retrospective review of ADH and ALH excision results after diagnosis by core needle biopsy Wendy Cornett Surgery Atypical Hyperplasia, Atypical Ductal Hyperplasia, Atypical Lobular Hyperplasia, Breast Cancer
Elucidating the Hemocompatability of Nanoparticles Jessica Larsen Clemson Research Nanoparticles, Hemocompatability, Blood, Polymersomes, nanomedicine, nanotechnology, drug delivery, hemolysis, coagulation, complement
Stress and Burnout in Greenville County EMS Paramedics and EMTs Lauren Fowler Neuroscience EMS, Burnout, Stress, Exhaustion, empathy
Complications after reverse shoulder arthroplasty lessening over time: A Retrospective Review of Complications Stephan Pill, MD Orthopaedics Reverse shoulder arthroplasty; complications
Robotic Resection of Mediastinal Parathyroid Masses William Bolton Surgery Mediastinum, robot-assisted thoracoscopic surgery, mediastinal mass resection, parathyroidectomy, davinci robot
Investigation of the polyol pathway in Entamoeba histolytica Cheryl Ingram-Smith Clemson Research Entamoeba histolytica, polyol pathway, aldose reductase, sorbitol dehydrogenase, fructokinase
The effects of prescribed psychotropic medications on patient baseline to end PHQ-9 and GAD-7 scores compared to the scores of patients that were not prescribed psychotropic medications within the Collaborative Care Model Karen Lommel Psychiatry Collaborative Care
Waist-Height Ratio (WHR) may predict loss of nocturnal dip on Ambulatory Blood Pressure Monitoring (ABPM) Sudha Garimella Pediatrics Waist-Height Ratio
Autism Care Network Karen Ratliffe-Schaub, MD Pediatrics Autism spectrum disorder
Provision of Blood Pressure Monitors to improve Hypertension Control and enhance patient self-management and empowerment Meenu Jindal Internal Medicine Motivational interviewing
Pancreatic Registry Christine Schammel, PhD Pathology Pancreatic fistula, pancreaticoduodenectomy, distal pancreatectomy, pancreatic leak, drain, drain amylase
Nutritional Optimization Prior to Bariatric Surgery John Scott Surgery Nutrition
Nutritional Optimization Prior to Bariatric Surgery John Scott Surgery Nutrition
Expression of members of the multi-protein SAGA chromatin modifying complex in blastocoel fluid-conditioned media from IVF-generated human embryos is associated with positive implantation status Renee Chosed Biomedical Sciences SAGA
Institutional Review of Meningiomas Christine Schammel Pathology Meningioma, Grade, Recurrence, outcomes, survival, incidental findings, gross total resection.
Creating A Medical School-Oriented Map of Immunologic Processes Jennifer Grier, PhD ITOR Medical School, Immunology, Human Immune System
Food Insecurity Among Health Professions Students in the USC School System Jennifer Trilk, PhD Biomedical Sciences medical students and food insecurity
Splenic Artery Embolization: A Non-Invasive Approach to Blunt Splenic Injury Christine Schammel Interventional Radiology splenic artery embolization, abdominal trauma, trauma, blunt splenic injury (BSI), blunt splenic trauma, proximal embolization, distal embolization, combined embolization, non operative management (NOM) of splenic trauma
Carotid Artery Calcifications in Patients 30-60 years of age: important indicator for radiologists to report? Christine Schammel Pathology Carotid Artery Plaque
Meningioma Christine Schammel Pathology outcomes, recurrences, grading, predisposition, symptoms, survival, imaging, medications
Exploratory Data Analysis of the ITOR Biorepository Jeffrey Edenfield, MD Cancer Institute Data Analysis, Retrospective, Oncology, Cancer, Biorepository
Young Infant Characteristics and Laboratory Findings Associated with the FilmArray Meningitis/Encephalitis Panel Nicholas Potisek, MD Pediatrics bacterial Meningitis/Encephalitis
Error Occurrence in Death Certification: A Health System Based Review Christine Schammel PhD Pathology Death certificate accuracy, cause-of-death, how to fill out a death certificate
Comparison of USP34 expression in preimplantation blastocoel fluid from IVF-generated embryos Renee Chosed - PhD Biomedical Sciences blastocyst
Connect for Health Pediatric Weight Management Program Patient Experience with Care Survey Kerry Sease, MD, MPH Pediatrics Childhood obesity, Connect for Health, pediatric weight management program, public health, patient experience
Telehealth: The New Approach to Routine Prenatal Care? Kristine Martin OBGYN Telehealth, Prenatal healthcare, Social determinants of health, accessibility, health outcomes
An Investigation of Burnout in Greenville County EMTs and Paramedics Lauren Fowler Neuroscience Emergency Medical Services, Paramedics, EMT, Fatigue, Burnout, Stress, MBI, Pupillometry, Shift Work
Community Health and Health Disparities in Pediatric Respiratory Virus Infections with SARS-CoV-2 and RSV in Upstate South Carolina Brooks McPhail Biomedical Sciences Community Health and Health Disparities in Pediatric Respiratory Virus Infections with SARS-CoV-2
Community Health and Health Disparities in Pediatric Respiratory Virus Infections with SARS-CoV-2 and RSV in Upstate South Carolina Jennifer Grier Biomedical Sciences Pediatric
Racial Disparities and Outcomes of Patients Undergoing Ventral Hernia Repair Alfredo Carbonell Surgery race, racial disparities, hernia surgery, ventral hernia, ventral hernia repair, health outcomes
Distinct subsets of SIDS infants as defined by inflammatory markers in the CSF; potential relationship to brainstem serotonergic abnormalities Robin Haynes, PhD Pathology Research - Boston Children's Hospital SIDS, brainstem, sudden infant death syndrome, inflammation, neuropathology, cerebral spinal fluid, neopterin, microglia, CNS inflammation
Correlation of marshmallow esophagram with high resolution manometry and clinical outcomes Dr. Shanu Kothari Surgery Minimally invasive surgery
Near Infrared Spectroscopy: Effects of Different Chemotherapy Regimens on Skeletal Muscle Mitochondrial Function in Breast Cancer Patients Dr. Jennifer Trilk Cancer Institute Oncology
Feasibility and Limited Efficacy of a Tandem Cycling Community Exercise Program on Physiological Health, Functional Health, Therapeutic Relationships, and Quality of Life in Persons and Care Partners affected by Parkinson’s Disease Jennifer Trilk Human Performance Lab Cycling, Parkinson's Disease, therapeutic relationship, exercise science
Improving Radiographic Data Capture for the Prisma Health Comprehensive COVID-19 Registry Smitty Heavner Internal Medicine Quality Improvement, COVID-19 Registry, Radiology, Data Abstraction, REDCap
Models of Access to Care for Immigrant Children Julie Linton Pediatrics Access to care
Fatigue Risk Management Strategies to Mitigate Elevated Levels of Fatigue in the Emergency Department Lauren Fowler Neuroscience Fatigue, Emergency Department, Fatigue Risk Management, Strategies, Emergency Physicians
Protein Purification of PEX 13.1 and 13.2 YG Rich Region and PEX 13.1 SH3 region Meredith Morris, PhD Clemson Research Project has been focused on developing a protocol for purification of these proteins to allow for immunoprecipitation assays with these proteins found in Trypanasoma brucei brucei.
UNDERSTANDING THE PERSPECTIVES AND NEEDS OF AFRICAN-AMERICAN AND LATINO CAREGIVERS OF PERSONS WITH ALZHIEMER’S DISEASE IN UPSTATE SOUTH CAROLINA – LatinX Perspectives Beliefs and Perceived Barriers Arm Melissa Bailey, DO, MPH Geriatric Medicine Caregiving; Caregiver; Latino; Hispanic; Dementia; Alzheimer's Disease; Alzheimer's Disease and related disorders; Health Disparities; Health Communication; Qualitative research
Molecular Characterization of Cancer Patient Tissues and Mutational Analysis Anna Blenda, PhD Biomedical Sciences glycan, neoplasm, tumor, mutation, breast cancer, lung cancer
Challenging Cases and Practical Approaches: Actinic Keratosis to Squamous Cell Carcinoma Progression Todd Schlesinger Dermatology - Clinical Research of the Carolinas Actinic Keratosis
The effect of patient centered lifestyle interventions on health knowledge and self-empowerment in patients with obesity. Meenu Jindal Internal Medicine empowerment, lifestyle medicine, exercise, education, health knowledge, obesity
Comparing Efficacies of Various Invasive and Non-invasive H. Pylori Detection Methods Christine Schammel Pathology H. pylori, efficacy, diagnostic tests
Error Occurrence in Death Certification: A Health System Based Review and Educational Intervention Outcome Analysis Christine Schammel, PhD Pathology death certificate accuracy, cause of death
Disparities in perinatal depression screening and referral Erica Schenhals OBGYN depression, disparities, perinatal, screening
Patient-Reported Outcomes Measurement Information System (PROMIS) Utilization for Needs Assessment and Clinical Service Improvement in a New Adolescent and Young Adult Program Aniket Saha Pediatrics Psychosocial needs, health related quality of life (HRQOL), patient-reported outcome, adolescent and young adult (AYA), Oncology
The Role of IFI27 in the Antiviral Immune Response to SARS-CoV-2 Jennifer Grier Biomedical Sciences IFI27
Synthesis of Novel Diazcylobutenes to Combat Trichomonas Vaginalis Dan Whitehead Clemson Research Organic Chemistry, Synthesis, Novel Molecule, Parasitic infection, Drug Development,
Toward Educating and Enabling Patients with Metastatic Breast Cancer in Shared-Decision-making Using mHealth Technology: Identifying Patient Therapeutic Goals and Preferences Melanie Cozad, PhD USC - Arnold School of Public Health metastatic breast cancer, shared decision-making, mHealth, technology, mobile app, patient preferences, goals, education, therapy, communication, oncology, point of care, treatment, management
Impact analysis of Visual Literacy training on improved patient-centered outcomes in telehealth settings: reducing medical error by targeting skills of observation, communication, empathy, and ambiguity tolerance Joy Shen-Wager Family Medicine Telehealth
Stroke prevention in atherosclerotic disease: A comparative study of transfemoral carotid artery stenting versus transcarotid artery revascularization Bruce Gray Surgery Stent; Surgery; Vascular; Transfemoral; Carotid
COVID-19’s Impact on the Latinx Community in Upstate SC: A qualitative inquiry examining the community perceptions of disparities that transpired during the peak and aftermath of COVID-19 infections in the Upstate Smitty Heavner-sullivan, RN Internal Medicine COVID-19
Laparoscopic Appendectomy Resource Utilization Shanu Kothari Surgery Surgical quality improvement, cost analysis
Stress and Fatigue among EMT Professionals Lauren Fowler Biomedical Sciences Cortisol, Stress, Fatigue, EMT, Empathy
Case Study: false positive dotatate uptake in the small bowel mesentery Christine Schammel Pathology Dotatate
Characterization of Hypothetical Protein EHI_056700 in E. Histolytica Lesly Temesvari Clemson Research Kinase, virulence, human pathogen research, infectious disease
Does Stroke Severity Affect Sensory-Feedback Needed for Volitional Movements? Michelle Woodbury MUSC, Department of Health Sciences and Research CVA, stroke, stroke recovery, rehabilitation, motor planning
The Effects of Illness Perception on Diabetes Control Meenu Jindal Internal Medicine illness perception; illness beliefs; type 2 diabetes; diabetes control; uncontrolled diabetes; IPQ-R
Pancreas Registry Christine Schammel- PhD Pathology Pancreatic Fistula
Screening and addressing the social determinants of health at the Internal Medicine Clinic Meredith Eicken MD, MPH Internal Medicine Social Determinants of Health, SDoH, Primary Care, Internal Medicine, Public Health, SDoH Screening, Addressing SDoH
Trypanosoma brucei PEX 13s YG-rich and SH3 regions: expression and purification Meredith Morris PhD Clemson Research Purification of PEX protein variants from Trypanosoma brucei parasites, to further study the structure and function of the proteins to understand their role in organism survival.
Non-alcoholic steatohepatitis (NASH) Elastography versus Liver Biopsy Christine Schammel Pathology Non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), ultrasound, CT, MRI, imaging, elastography, biopsy, metabolic, hepatomegaly, steatosis, fibrosis, cirrhosis, diagnosis, prognosis, scoring, staging, risk, management, treatment
The Role of Medical Student Notes within the Emergency Department Team Page Bridges, MD Emergency Medicine Emergency Medicine
Rates of Preventative Cancer Screenings in Patients with Opioid Use Disorder: Recommendations to Close Gaps in Care Heather Delisi North Shore Community Health Center Peabody Opioid Use Disorder (OUD), Medication for Addiction Treatment (MAT), Community Health Center (CHC)
Synthesis of a novel siderophore antibiotic Steven Fiester PhD Biomedical Sciences antibiotics, siderophore, organic chemistry
Patient Engagement in Fertility Research: Bench Research, Ethics, and Social Justice Melanie Cozad USC - Arnold School of Public Health PPI, ethics, social justice, IVF, patient engagement
The role of pharmacogenomics in the medical management for Native Americans and Caucasian kidney transplant recipients Mira Keddis MD Nephrology Nephrology
An Overview of Coronavirus and Type 2 Diabetes Mellitus Meenu Jindal Internal Medicine Diabetes
The correlation between abnormal uterine bleeding and female sexual dysfunction Lisa Green, MD, MPH OBGYN sexual dysfunction, abnormal uterine bleeding, obgyn, AUB
Validation of a labor induction calculator Lisa Green, MD, MPH OBGYN labor, induction, obgyn
Reducing miscarriage rates via molecular analysis of preimplantation blastocel fluid Renee Chosed Biomedical Sciences In Vitro Fertilization, IVF, Miscarriage, Blastocel fluid, Implantation,
Computational Analysis of the Diagnosis and/ of Prognosis from the Perspective of the Ovarian Cancer Patient Young Ji Lee, PhD, MS, RN Univeristy of Pittsburgh School of Medicine Department of Biomedical Informatics Python, ovarian cancer, cancer diagnosis, cancer prognosis, personalized medicine, online forum
Evaluation of gastrostomy tube placement, feeding strategies, and speech Robert Ricca Surgery pediatric, surgery, gtube, speech therapy, reevaluation, complication, duration of gtube placement
Impact of initial hernia repair technique and mesh location on outcomes of Subsequent Abdominal Operations Jeremy Warren, MD Surgery hernias, general surgery, mesh placement, subsequent abdominal operations
The Effect of Polymersomes on Blood Components Jessica Larsen Clemson Research Blood Components, polymersomes, nanoparticles, drug delivery devices PEG-PLA, PEG-PLGA
The role of hippocampal seizures in SIDS Robin Haynes PhD Pathology Research - Boston Children's Hospital Sudden Infant Death Syndrome, Hippocampus, Neuropathology, Sudden Unexpected Death in Childhood, SUDC, SIDS, brainstem, serotonin
Analysis of medical students after exposure to FAVOR recovery coaches in the emergency department. Erik Fisher, MD Emergency Medicine FAVOR, Faces and voices of recovery, Substance use disorder, SUD, empathy, medical students, survey
the relationship between sagittal abdominal diameters and ambulatory blood pressures Sudha Garimella Pediatrics Sagittal abdominal diameters
Project COPE Ann Kennedy USCSOMG N/A
MFMU COVID-19 Registry Allison Moore, RN, BSN, CCRC OBGYN COVID-19, pregnancy, GRAVID, NIH, MFMU
Polysubstance use and effects on mothers and infants Mary Ellen Wright, PhD Clemson Research Polysubstance use, substance use disorder, SUD, neonatal abstinence syndrome, NAS
Pharmacogenetic evaluation for kidney disease and transplantation Mira Keddis MD Mayo Clinic AZ Pharmacogenetics
Measuring muscle mitochondrial oxidative capacity with Near-infrared spectroscopy in person with cancer undergoing chemotherapy Jennifer Trilk, Ph.D, FACSM, DipACLM Cancer Institute Chemotherapy, exercise, oxidative capacity, Near-infrared spectroscopy
Galectin-3 and its correlation with rs1870377 Anna Blenda Biomedical Sciences galectins, cancer, VEGFR, VEGFR-2, KDR, galectin-3

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