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School of Medicine Greenville


Faculty Profile

Faculty and Staff

Richard Lance Goodwin, Ph.D.

Title: Professor
Biomedical Sciences
School of Medicine Greenville
E-mail: goodwirl@greenvillemed.sc.edu
Phone: 864-455-7476
   
Office: 701 Grove Road
Greenville SC
profile

Bio

Background: Since completing my postdoctoral training with Dr. David Bader, I have established a research program that investigates mechanisms of embryonic development and disease. My lab has generated in vitro 3D models of the development of cardiovascular tissues including myocardial, valve and vessel development. This work has resulted in numerous publications and has been supported by funding from NIH, NSF, Biotech Research Partnerships, and Private Foundations. These studies have lead to additional research interests in the development of fibrous tissues, which occurs normally during embryonic development and pathologically in a number of disease processes. Current projects include 3D models of vessel disease and multiple myeloma progression.
Teaching Interest(s): Medical Embryology Medical Histology Anatomy Developmental Biology and Regeneration Cardiovascular Developmemt
Research Interest(s): My research interests include the mechanisms that regulate the initial formation of tissues during development as well as pathological processes such as those that occur in cancer and fibrosis. To study these mechanisms in detail, my lab has generated in vitro models of development and disease that recreate the three-dimensional and mechanical environments of in vivo tissues. Using a flexible biofabrication system, we have generated dynamic, 3D models of myocardial, valvular, and vascular histogenesis. Current projects include fabrication of human 3D models of vascular disease, fibrotic remodeling, and cancer. The goal of this research is to determine the key regulating factors of these pathologies so that they may be therapeutically targeted. In caring out these studies, we simultaneously advance our mechanistic understanding of tissue homeostasis and pathogenesis as well as develop a test bed to screen new molecular and cell based therapies.
Honors & Awards: Paper of the Year
'String of Pearls'Medical Student Teaching Award
'String of Pearls'Medical Student Teaching Award
'String of Pearls'Medical Student Teaching Award
'String of Pearls'Medical Student Teaching Award
Professional Affiliations: Microscopic Society of America
Member
NIH Special Emphasis Panel/Scientific Review Group 2015/01 ZRG1 CVRS-Q (80) A
Member
NIH Special Emphasis Panel/Scientific Review Group 2015/05 ZRG1 BCMB-A (51) R
Member
NIH Special Emphasis Panel/Scientific Review Group 2014/10 ZRG1 CVRS-Q (80) A
Member
NIH Special Emphasis Panel/Scientific Review Group 2013/01 ZRG1 CVRS-K (90)
Member
NIH Special Emphasis Panel/Scientific Review Group 2013/01 ZRG1 CVRS-N (02_ M
Member
NIH Special Emphasis Panel/Scientific Review Group 2013/05 ZRG1 BCMB-A (51) R
Member
NIH NHLBI Ad Hoc Program Project Study Section
Member
American Association of Anatomists
Member
Biomedical Engineering Society
Member
NIH Transformative Research Award program of the NIH Director's Common Fund study section
Member
American Heart Association NAtional Basic Cell and Molecular Biology 2 Study Section
Member
American Heart Association Northeast Affiliate Study Section (ad hoc)
Member