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Academic Advising

Chemistry – Bachelor of Science (B.S.)

McCausland College of Arts and Sciences
Department of Chemistry & Biochemistry
Bulletin Year: 2026-2027

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Important: This course plan is a recommended sequence for this major. Courses designated as critical (!) may have a deadline for completion and/or affect time to graduation. Please see the program notes section for details regarding “critical courses” for this particular Program of Study.

Semester One (17 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
! ENGL 101 Critical Reading and Composition (CC-CMW) 3 C    
  MATH 141 Calculus 1 (CC-ARP)3 4     C or better in Math 112/115/116 or through placement exam
  CHEM 141 Principles of Chemistry I (PR)4 3     C or higher in MATH 111 or placement into MATH 115 or higher MATH; Prereq or Coreq: C or higher in CHEM 141L
  CHEM 141L Principles of Chemistry I Laboratory (PR)4 1     C or higher in MATH 111 or placement into MATH 115 or higher MATH; Prereq or Coreq: C or higher in CHEM 141
    Foreign Language5 or other Carolina Core6 (CC-GFL) 3      
  UNIV 101 The Student in the University or Carolina Core Requirement6 (PR/CC) 3      

Semester Two (18 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
! ENGL 102 Rhetoric and Composition (CC-CMW, CC-INF) 3 C   C or better in ENGL 101
  MATH 142 Calculus II (CC-ARP) 4     C or better in MATH 141
! CHEM 142 Principles of Chemistry II (PR)4 3     C or higher in MATH 115 (or by placement score into MATH 141 or higher); C or higher in CHEM 141 or CHEM 112; Prereq or Coreq: C or higher in CHEM 142L
  CHEM 142L Principles of Chemistry II Laboratory (PR)4 1     C or higher in MATH 115 (or by placement score into MATH 141 or higher); C or higher in CHEM 141 or CHEM 112; Prereq or Coreq: C or higher in CHEM 142
  PHYS 211 Essentials of Physics I (CC-SCI) 3 C   C or better in MATH 141; Coreq: PHYS 211L
  PHYS 211L Essentials of Physics I Lab (CC-SCI) 1 C   Prereq or Coreq: C or better in PHYS 211
    Foreign Language5 or other Carolina Core6 (CC-GFL) 3      

Semester Three (15 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
  MATH 241 Vector Calculus (PR)7 3     C or better in MATH 142
  CHEM 333 Organic Chemistry I (MR) 3 C   C or higher in CHEM 112 or 142
  CHEM 333L Comprehensive Org. Chem. Lab I (MR) 2 C   C or better in CHEM 112L or CHEM 142L; Pre/Coreq: C or higher in CHEM 333
  PHYS 212 Essentials of Physics II (CC-SCI)7 3 C   C or better in PHYS 211 & MATH 142; Coreq: PHYS 212L
  PHYS 212L Essentials of Physics II Lab (CC-SCI)7 1 C   Prereq/Coreq: C or better in PHYS 212
    Foreign Language5 or Carolina Core Req.6 (CR/CC) 3      

Semester Four (15 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
  CHEM 322 Analytical Chemistry (MR) 3 C   C or higher in CHEM 112 or CHEM 142; C or higher in MATH 111 or higher (or placement in MATH 115 or higher); Coreq: C or higher in CHEM 332L
  CHEM 322L Analytical Chemistry Lab (MR) 1 C   C or higher in CHEM 112L or CHEM 142L; Pre/Coreq: C or higher in CHEM 322
  CHEM 334 Organic Chemistry II (MR) 3 C   C or better in CHEM 333
  CHEM 334L Comprehensive Org. Chem. Lab II (MR) 2 C   C or higher in CHEM 333L; Coreq: CHEM 334
    History8 (CR) 3      
    Carolina Core Requirement6 (CC) 3      

Semester Five (17 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
    CHEM Elective9 (MR) 3 C   See Bulletin listing
  CHEM 541 or CHEM 542 Physical Chemistry (MR) 3 C   See Bulletin listing
  CHEM 541L or CHEM 542L Physical Chemistry Lab (MR, CC-INT) 2 C   See Bulletin listing
  STAT 509 or STAT 515 Statistics for Engineers or Statistical Methods I7&10 or Elective11 (CR) 3     MATH 142 (STAT 509); C or better in MATH 112/115/122 or 141; or both C or better in STAT 110 or higher and in MATH 111; or through placement exam (STAT 515)
    Cognate or Minor Course7 or Elective11 (PR) 3 C (minor)    
    Humanities or Fine Arts (CR) 3      

Semester Six (14-15 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
  CHEM 541 or CHEM 542  Physical Chemistry (MR) 3 C   See Bulletin listing
  CHEM 541L or CHEM 542L  Physical Chemistry Lab (MR, CC-INT) 2 C   See Bulletin listing
  CSCE 106 or CSCE 145 Scientific Applications Programming or  Algorithmic Design I (CR) 3-4     C or better in MATH 111 or higher (or by placement exam into MATH 115 or higher) (CSCE 106); Prereq/Coreq: MATH 111 or 115 (CSCE 145)
    Cognate or Minor Course7 or Elective11 (PR) 3 C (minor)    
    Carolina Core Requirement6 (CC) 3      

Semester Seven (12 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
    Cognate or Minor Course7 or Elective (PR)11 3 C (minor)    
    Cognate or Minor Course7 or Elective (PR)11 3 C (minor)    
    Social Science (CR) 3      
    Carolina Core Requirement6 or Elective11 (CC/PR) 3      

Semester Eight (12 Credit Hours)

Critical Course Code Subject and Title Credit Hours Min. Grade1 Major GPA2 Prerequisites
    Minor Course7 or Elective11 (PR) 3 C (minor)    
    Minor Course7 or Elective11 (PR) 3 C (minor)    
    Carolina Core Requirement6 or Elective11 (CC/PR) 3      
    Elective11 (PR) 3      

Graduation Requirements Summary

Minimum Total Hours Minimum Major Requirements Hours College and Program Requirements Hours Carolina Core Hours Minimum Institutional GPA
120 27 47-60 34-46 2.000
  1. Regardless of individual course grades, students must maintain a minimum 2.000 cumulative GPA.
  2. Some colleges require a minimum GPA for major courses. Courses indicated in this column are included in the major GPA for this program of study.
  3. Students who do not place into MATH 141 will be required to successfully complete MATH 112, 115, or 116 before taking MATH 141.
  4. CHEM 111 and CHEM 111L may be taken in place of CHEM 141 and 141L, and CHEM 112 and CHEM 112L may be taken in place of CHEM 142 and 142L.
  5. Students in the McCausland College of Arts and Sciences are required to demonstrate proficiency in one foreign language equivalent to the 122 course through course credit or the corresponding foreign language placement score.
  6. The Carolina Core provides the common core of knowledge, skill and academic experience for all Carolina undergraduate students.
  7. The cognate is intended to support the course work in the major. The cognate must consist of twelve hours of courses at the advanced level, outside of, but related to the major. In place of a cognate, a student may choose a minor consisting of at least 18 credit hours of courses concentrated in one area that follow a structured sequence. All minor courses must be passed with a grade of C or higher. For B.S. degrees, grades of D are acceptable for completion of the cognate requirement, except where restricted by the major program. A second major eliminates the minor/cognate requirement. Students may use MATH 241, STAT 509/515, and PHYS 212 and 212L toward the cognate requirement but would need to complete additional electives to meet hours to graduate.
  8. The McCausland College of Arts and Sciences requires one U.S. History and one non-U.S. History course, both of which must be chosen from the approved Carolina Core GHS courses. Whichever is not fulfilled through the Carolina Core GHS requirement must be fulfilled through this college requirement.
  9. CHEM Electives (3 hours): CHEM 511, 533, 545, 550, 555, 621, 623, 624, 633, 644.
  10. If CHEM 141, 142, 322, and 322L are all completed at USC, STAT 509 or 515 is not required. Also, if CHEM 621 and 621L are completed, STAT 509 or 515 is not required. Students who exempt STAT 509 or 515 through this process will be required to take an approved elective to reach minimum hours for graduation.
  11. No courses of a remedial, developmental, skill-acquiring, or vocational nature may apply as credit toward degrees in the McCausland College of Arts and Sciences. The McCausland College of Arts and Sciences allows the use of the Pass-Fail option on elective courses. Further clarification on inapplicable courses can be obtained from the McCausland College of Arts and Sciences.

Program Notes

  • ENGL 101 and ENGL 102 must be completed in the student’s first 60 semester hours of work in order for these courses to be credited toward graduation. CHEM 142 is a prerequisite for subsequent required courses and may delay progression if not taken in a timely manner.
  • All undergraduate students must take a 3-credit course or its equivalent with a passing grade that covers the founding documents. This course may fulfill any requirement in the program of study. Courses that meet this requirement are listed in the academic bulletin.
  • Any Chemistry or Biochemistry and Molecular Biology major can qualify for ACS certification by taking additional courses as listed: CHEM 511, CHEM 621, CHEM 621L, CHEM 550 or CHEM 555, and 6 credits of undergraduate research, CHEM 496-499.
  • CHEM 401 Industrial Chemistry Capstone Experience is a recommended elective that prepares students for future roles in chemistry.
  • Chemistry majors may enroll in a chemistry course a maximum of twice to earn the required grade of C or higher.
  • A Chemistry major must receive a grade of C or higher in any chemistry course in order for it to be used to satisfy a major requirement.
  • The last 30 credit hours toward your degree must be earned in residence at the University of South Carolina-Columbia.

Code Definitions

University Requirements: Bachelor’s degree-seeking students must meet Carolina Core (general education) requirements.

Code Definition
CC Carolina Core
CC-AIU Carolina Core – Aesthetic and Interpretive Understanding
CC-ARP Carolina Core – Analytical Reasoning and Problem-Solving
CC-CMS Carolina Core – Effective, Engaged, and Persuasive Communication: Spoken Component
CC-CMW Carolina Core – Effective, Engaged, and Persuasive Communication: Written Component
CC-GFL Carolina Core – Global Citizenship and Multicultural Understanding: Foreign Language
CC-GHS Carolina Core – Historical Thinking
CC-GSS Carolina Core – Social Sciences
CC-INF Carolina Core – Information Literacy
CC-INT Carolina Core – Integrative Course
CC-SCI Carolina Core – Scientific Literacy
CC-VSR Carolina Core – Values, Ethics, and Social Responsibility
CR College Requirement
MR Major Requirement
PR Program Requirement

Disclaimer: Major maps are only a suggested or recommended sequence of courses required in a program of study. Please contact your academic advisor for assistance in the application of specific coursework to a program of study and course selection and planning for upcoming semesters.


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