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College of Engineering and Computing

Biomedical Engineering

Identifying Patient-specific Risk Factors for Large Vessel Ischemic Stroke


The project focuses on relating computed hemodynamic stresses acting on carotid atherosclerotic plaques, based on patient-specific CT images, to gene and protein expression levels in human endarterectomy specimens.  Mechanical behavior of the excised plaques is also characterized.  This is a collaborative effort with vascular surgeons at Greenville Hospital System.


T. Benzing, C. Wilhoit, S. Wright, P. A. McCann, S. Lessner, and T. E. Brothers, "Standard Duplex Criteria Overestimate the Degree of Stenosis after Eversion Carotid Endarterectomy," J. Vasc. Surg., 61(6), 1457–1463 (2015).