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  NIH: Mutant Mouse Resource and Research Centers (U42)RFA-OD-14-003

This Funding Opportunity Announcement (FOA) invites applications for the continued support and advancement of the Mutant Mouse Resource and Research Centers, MMRRC (former Mutant Mouse Regional Resource Center program). The MMRRC consortium is expected to facilitate research by identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. A regional network of four MMRRCs and an Informatics, Coordination and Service Center (ICSC) collectively serves the needs of the biomedical research community for transgenic, knockout and other genetically-engineered mutant mice and related biomaterials. The MMRRC consortium uses mutually agreed upon, defined standard operating procedures. Each MMRRC is responsible for importing mice from assigned donating investigators, and establishing banks of cryopreserved sperm, embryos, and related materials for distribution to research investigators. Each center also provides services on a fee-for-service basis which include such specialties as cryopreservation of mouse embryos and gametes, rederivation of living mice from cryopreserved embryos and sperm, quality control testing for mouse pathogens, mutagenesis and embryonic stem cell isolation and cloning, phenotyping and genotyping services. The Program Director/Principal Investigator (PD/PI) of each MMRRC is required to develop a high risk, high return, research pilot that complements the goals and needs of the MMRRC consortium. Examples of projects include, but are not limited to: improvement of methods for mouse cloning, preserving germplasm, health monitoring, testing for mouse pathogens, assisted reproductive technologies, phenotyping, developing new mouse models of human disease, genotyping services, or deriving ES cell lines.

USC may only submit one application in response to this program announcement. Your application submission MUST be coordinated with the Office of the Vice President for Research. Please send a two page abstract via email to Richard White ( ) by April 3, 2014. In addition to the 2-page abstract, you should also submit a biosketch for the PI.

NIH indicates that a letter of intent is NOT applicable and a full proposal is due by May 1, 2014. For more information:
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