Graduate Index		Farid Sadik, Dean Michael Dickson, Chair, Department of Pharmaceutical and Health Outcomes Sciences Joseph W. Kosh, Chair, Department of Basic Pharmaceutical Sciences, and Director of Graduate Studies Professors Michael Dickson, Ph.D., Ohio State University, 1972 Joseph W. Kosh, Ph.D., University of Colorado, 1971 C. Eugene Reeder, Ph.D., University of South Carolina, 1983 Joseph Roberts, Ph.D., McGill University, 1964 Farid Sadik, Ph.D., University of Mississippi, 1968 Richard M. Schulz, Ph.D., University of North Carolina, 1983 J. Walter Sowell, Ph.D., University of Georgia, 1972 Associate Professors Sondra H. Berger, Ph.D., Roswell Park, State University of New York at Buffalo, 1982 James M. Chapman, Ph.D., University of North Carolina, 1981 Earle W. Lingle, Ph.D., University of Texas, 1985 Assistant Professors Theresa J. Smith, Ph.D., Texas Women’s University, 1988 Desuo Wang, Ph.D., University of Florida, 1995 Michael D. Wyatt, Ph.D., University College London, 1996 Bao Ting Zhu, Ph.D., University of Texas Medical Branch, 1992 Faculty Emeritus Robert L. Beamer, Ph.D., Medical College of Virginia, 1959 Overview The College of Pharmacy is accredited by the American Association of Colleges of Pharmacy and the Southern Association of Colleges and Schools. The college offers a program leading to the M.S. degree in pharmaceutical sciences. The Colleges of Pharmacy of the University of South Carolina and the Medical University of South Carolina offer a jointly administered program leading to the Ph.D. degree in pharmaceutical sciences. At the University of South Carolina, areas of research specialization include medicinal chemistry, pharmaceutics, pharmacology, and pharmacy administration. At the Medical University of South Carolina, areas of research specialization include natural products/pharmaceutical chemistry, pharmaceutics, and industrial pharmaceutical technology. Several specialized course offerings are available by closed-circuit/talk-back TV using faculty from both campuses. The College of Pharmacy at the University of South Carolina is composed of the Department of Basic Pharmaceutical Sciences and the Department of Pharmaceutical and Health Outcome Sciences. The Department of Basic Pharmaceutical Sciences offers advanced degrees with specialization in the areas of medicinal chemistry, pharmaceutics, and pharmacology. The Department of Pharmaceutical and Health Outcome Sciences offers advanced degrees with specialization in the area of pharmacy administration. A graduate admissions committee of the college reviews all applicants to the M.S. and Ph.D. programs. Candidates may apply for admission at any time during the year; however, notification of acceptance will normally be made only in March for matriculation the following fall semester. Serious consideration will be given to applicants with a minimum overall grade point average equivalent of B and a minimum score of 1575 (verbal, quantitative, and analytical) on the GRE. In addition, international students must score a minimum of 570 (230 computer-based score) on the TOEFL exam. A degree from an accredited college of pharmacy is required for applicants considering an advanced degree in the discipline of Pharmaceutical and Health Outcome Sciences. For advanced degrees in the disciplines of medicinal chemistry, pharmaceutics, or pharmacology, an undergraduate degree in pharmacy or in the supporting sciences, such as chemistry or biology, is recommended. Requests for information regarding programs, policies, and the admission process can be submitted electronically via the Web site of the University of South Carolina at www.sc.edu/prospective/html. The college awards a number of teaching and/or research assistantships to graduate students in Basic Pharmaceutical Sciences and Pharmaceutical and Health Outcome Sciences. The award is based upon academic promise and has a highly competitive annual stipend. Recipients also receive a reduction in University fees and tuition. Students receiving graduate stipends are subject to regulations of The Graduate School and the following policies: 1. Supported students must enroll for at least six semester hours of credit each semester and at least one semester hour each summer term. 2. Assistantships shall be canceled for students who do not perform their assigned duties satisfactorily. 3. Assistantships shall be canceled for students who do not demonstrate quality performance in their academic program. To receive a graduate stipend students must also meet The Graduate School criteria for progression. 4. Students generally will not be supported for more than one year beyond the semester they are eligible to stand for the Ph.D. comprehensive examination or for four years, whichever is less.   Department of Basic Pharmaceutical Sciences Joseph W. Kosh, Chair of the Department Overview The Department of Basic Pharmaceutical Sciences offers M.S. and Ph.D. degrees in pharmaceutical sciences with a primary research focus in either biomedicinal chemistry, synthetic medicinal chemistry, pharmaceutics, or pharmacology. The M.S. and Ph.D. programs are structured to accommodate diverse individual research interests. The student, in consultation with an advisor and advisory committee, will develop a program of study to be approved by the director of graduate studies. Candidates for either degree are expected to conduct original basic research and to make a contribution to the literature in their area of expertise. Therefore, in order to completely satisfy all departmental requirements for the degree, all M.S. and Ph.D. candidates must submit a thesis or dissertation as appropriate as well as manuscripts prepared for submission for publication. Graduates of the program are expected to be pharmaceutical scientists. Therefore, students are exposed to interdisciplinary training and education while seeking an advanced degree in pharmaceutical sciences. Students completing the program of study develop an appreciation and understanding of the processes involved in developing, testing, and evaluating clinical applications of new medicinal agents. Topics stressed in this process include synthesis and design of new medicinal agents; examination of the biochemical, pharmacological, and toxicological actions; bioavailability and excretion; and dosage formulations. Exposure of students to interdisciplinary training begins in the first year of enrollment with a common course core in medicinal chemistry, pharmaceutics, and pharmacology. Upon completion of the core, the student, in consultation with the major advisor and advisory committee, takes additional courses focused on a discipline of interest. Further interdisciplinary training is obtained by completing required didactic courses with team-taught recitation sections and by participation in the departmental seminar program. Candidates with an advanced degree(s) in pharmaceutical sciences will be prepared for a variety of career choices. These include teaching and research at academic institutions, research in the pharmaceutical industry, pharmaceutical sales, regulatory governmental agencies such as the Food and Drug Administration and toxicology laboratories, drug information consultation, and drug and law enforcement. Admissions Admission to the M.S. and Ph.D. degree programs in the area of medicinal chemistry, pharmaceutics, and pharmacology is available to students with a degree in biology, chemistry, or pharmacy from an accredited college or university. Students who do not have a degree in pharmacy should have completed satisfactorily the following undergraduate courses: one year each of general and organic chemistry, one year of physics, and mathematics through calculus. Students applying for pharmaceutics and medicinal chemistry are also required to have one year of physical chemistry. Those applicants with a nonpharmacy background may also be required to successfully complete degree-appropriate undergraduate courses in pharmacy and medicinal chemistry after admission to The Graduate School. Degree Requirements The Department of Basic Pharmaceutical Sciences awards the M.S. and Ph.D. degrees with the following emphases: synthetic medicinal chemistry, biomedicinal chemistry, pharmaceutics, and pharmacology. All students, in consultation with their major advisor and advisory committee, must develop an individualized program of study during their first year of enrollment in either degree program. All students must take six hours of core pharmacy courses (PHAR 703, 725, 738) for credit. A minimum of 12 hours of 700-level credit must also be earned in graduate pharmacy subjects in both degree programs. Students must complete the PHAR 712 series of courses (departmental seminar) and present one seminar each fall and spring semester while in the degree program. All graduate students specializing in pharmaceutics who have not successfully completed two semesters of physical chemistry (CHEM 541 and 542) must do so during their first year of residence. Graduate students specializing in medicinal chemistry who have not successfully completed at least one semester of physical chemistry must take CHEM 541 during their first year of residence. Students with prior graduate course work may transfer up to nine semester hours for graduate credit. Normally, the average minimum length of time required to complete the M.S. degree is two years, and five years for the Ph.D. degree. Further degree-specific requirements are found in the M.S. and Ph.D. degree requirements listed below. M.S. Degree Requirements All students must be admitted to candidacy to pursue the M.S. degree in the Department of Basic Pharmaceutical Sciences. Admission to candidacy for the M.S. degree is a two-part process. Part one is satisfied by successful completion of six hours of core courses (PHAR 703, 725, and 738). Part two is satisfied in the second or third semester of the student’s program of study. Requirements for part two include selection of a research advisor and graduate committee, submission of an initial research proposal, and submission of a master’s program of study. A comprehensive written examination must also be taken after completion of all course requirements. Finally, a seminar based on the student’s thesis must be presented, followed by an oral defense of the thesis. In addition to the general requirements listed above, candidates for the M.S. degree are also required to complete two departmental seminar courses (PHAR 712A and 712B). A maximum of two hours credit can be earned for PHAR 712. All students are required to submit a thesis based upon original research that meets all requirements of The Graduate School and a manuscript(s) for publication prior to award of the degree. No more than six hours of credit for PHAR 799 will be allowed for thesis research and writing. Further degree requirements for each specialty area are listed below. M.S.–Medicinal Chemistry–Biomedicinal Prerequisite Courses BIOL 460 3 hrs. CHEM 541 3 hrs. Required Courses CHEM 550* 3 hrs. CHEM 751, 752, or 753 6 hrs. (3 each) PHAR 703 2 hrs. PHAR 704 3 hrs. PHAR 705 5 hrs. PHAR 712A, B 2 hrs. PHAR 725 2 hrs. PHAR 738 2 hrs. PHAR 799 6 hrs. Total 31 hrs. *If a student qualifies in biochemistry, CHEM 550 may be replaced by a didactic elective approved by his or her graduate committee. M.S.–Medicinal Chemistry–Synthetic Prerequisite Courses BIOL 460 3 hrs. CHEM 541 3 hrs. Required Courses CHEM 550* 3 hrs. PHAR 703 2 hrs. PHAR 704 3 hrs. PHAR 705 5 hrs. PHAR 706 3 hrs. PHAR 712A, B 2 hrs. PHAR 725 2 hrs. PHAR 738 2 hrs. PHAR 799 6 hrs. Approved Didactic Elective 3 hrs. Total 31 hrs. *If a student qualifies in biochemistry, CHEM 550 may be replaced by a didactic elective approved by his or her graduate committee. M.S.–Pharmaceutics Prerequisite Courses BIOL 243 3 hrs. BIOL 244 3 hrs. STAT 201 3 hrs. Required Courses CHEM 541 3 hrs. CHEM 542 3 hrs. CHEM 550 or CHEM 632 3 hrs. PHAR 703 2 hrs. PHAR 712A, B 2 hrs. PHAR 720 3 hrs. PHAR 725 2 hrs. PHAR 726 3 hrs. PHAR 738 2 hrs. PHAR 799 6 hrs. Total 38 hrs. M.S.–Pharmacology Prerequisite Course BIOL 460 3 hrs. Required Courses PHAR 703 2 hrs. PHAR 712A, B 2 hrs. PHAR 725 2 hrs. PHAR 736 1 or 4 hrs. PHAR 737 1 or 4 hrs. PHAR 738 2 hrs. PHAR 799 6 hrs. Approved Didactic Electives 8—20 hrs. Total 30—36 hrs. Ph.D. Degree Requirements All students must be admitted to candidacy to pursue the Ph.D. degree in the Department of Basic Pharmaceutical Sciences. Admission to candidacy for the Ph.D. degree in the department is a two-part process. Part one is satisfied by successful completion of the core courses (PHAR 703, 725, and 738). During the second semester, a research advisor and graduate committee must be selected. Part two is completed in the third semester by submission of a doctoral program of study form and an initial research proposal, which must be presented and defended to the student’s graduate committee. In semesters four through six, a comprehensive examination must be satisfied by submission and defense of an NIH-style research proposal. Finally, a seminar based on the student’s dissertation must be presented, followed by an oral defense of it. In addition to the general requirements listed above, candidates for the Ph.D. degree are required to complete four departmental seminar courses (PHAR 712A—D). A maximum of four hours credit can be earned for PHAR 712. All students are required to submit a dissertation based upon original research, meeting all requirements of The Graduate School, and a manuscript(s) for publication prior to award of the degree. No more than 12 hours of credit for PHAR 899 will be allowed for dissertation research and writing. Further degree requirements for each specialty area are listed below.   Ph.D.–Medicinal Chemistry–Biomedicinal Prerequisite Courses BIOL 460 3 hrs. CHEM 541 3 hrs. CHEM 542 3 hrs. Required Courses CHEM 550* 3 hrs. CHEM 751 3 hrs. CHEM 752 3 hrs. CHEM 753 3 hrs. PHAR 703 2 hrs. PHAR 704 3 hrs. PHAR 705 5 hrs. PHAR 712A—D 4 hrs. PHAR 725 2 hrs. PHAR 738 2 hrs. PHAR 899 12 hrs. Approved Didactic Electives** 6 hrs. Total 48 hrs. *If a student qualified in biochemistry, CHEM 550 may be replaced by a didactic elective approved by his or her graduate committee. **One didactic elective should be BIOL 655 (Biotechnology) or PHAR 714 (Drug Design by Molecular Modeling and Computational Techniques). Ph.D.–Medicinal Chemistry–Synthetic Prerequisite Courses BIOL 460 3 hrs. CHEM 541 3 hrs. CHEM 542 3 hrs. Required Courses CHEM 550* 3 hrs. PHAR 703 2 hrs. PHAR 704 3 hrs. PHAR 705 5 hrs. PHAR 706 3 hrs. PHAR 712A—D 4 hrs. PHAR 725 2 hrs. CHEM 735 3 hrs. CHEM 736 3 hrs. PHAR 738 2 hrs. PHAR 899 12 hrs. Approved Didactic Electives 6 hrs. Total 48 hrs. *If a student qualifies in biochemistry, CHEM 550 may be replaced by an elective approved by his or her graduate committee. Ph.D.–Pharmaceutics Prerequisite Courses BIOL 243 3 hrs. BIOL 244 3 hrs. STAT 201 3 hrs. Required Courses BIOL 620* 3 hrs. BIOL 655 3 hrs. CHEM 541 3 hrs. CHEM 542 3 hrs. CHEM 550 or CHEM 632 3 hrs. PHAR 703 2 hrs. PHAR 712A—D 4 hrs. PHAR 720 3 hrs. PHAR 725 2 hrs. PHAR 726 3 hrs. PHAR 738 2 hrs. PHAR 899 12 hrs. Didactic Electives 6 hrs. Total 49 hrs. *or approved comparable course Ph.D.–Pharmacology Prerequisite Course BIOL 460 3 hrs. Required Courses PHAR 703 2 hrs. PHAR 712A—D 4 hrs. PHAR 725 2 hrs. PHAR 736 1 or 4 hrs. PHAR 737 1 or 4 hrs. PHAR 738 2 hrs. PHAR 899 12 hrs. Didactic Elective Courses 13—26 hrs. Total 43—50 hrs.   Department of Pharmaceutical and Health Outcome Sciences Michael Dickson, Chair of the Department Overview The M.S. and Ph.D. programs are structured to accommodate diverse individual research interests. The student, in consultation with an advisor and advisory committee, develops a program of study to be approved by the director of graduate studies. The program includes course work as well as successful completion of a qualifying examination, written comprehensive examination, oral comprehensive examination, and defense of a dissertation based on original investigation. The societal role of pharmacy is drug use control. The graduate specialization of pharmacy administration is viewed as the area within pharmacy that researches issues related to the use and control of pharmaceuticals. Faculty and students pursue research in a variety of areas, yet all research has drug use and/or its control as the unifying framework. The objective of the graduate program is to develop in graduate students the knowledge base and skills necessary for them to conduct independent research in the area of pharmacy administration. The program will prepare students to assume positions in academia, government, or industry and to address important issues related to the use of pharmaceuticals in society. Specifically, the program is structured to give graduates the ability to initiate and conduct theoretical and applied research, including development of research protocols, data collection, interpretation, and reporting conclusions to groups in seminars and/or publications; to develop skills necessary for self-directed professional growth; and to develop the knowledge base necessary for expertise in the major and minor areas. Admissions In addition to the admissions standards listed above in the college "Overview," two letters of recommendation (preferably one from an immediate supervisor if the student is employed) are required. Additional courses may be required depending on a student’s academic background. Recent pharmacy graduates usually have completed background courses covering the health care system. Students without this background will need to take introductory courses in deficiency areas before taking graduate work in this field. An assessment of the student’s background and course needs will be made prior to or at the time of admission. Students usually take three or four graduate courses each semester, although the course load may vary due to individual circumstances. An admission to candidacy exam, sometimes called a qualifying exam, is required. Procedures for the exam are outlined in the Graduate Studies Bulletin. M.S. Degree Requirements Prerequisite Course PHRM 547 3 hrs. Required Courses ACCT 502 3 hrs. BADM 751 3 hrs. ECON 526 3 hrs. MGMT 718T 3 hrs. PHAR 711A, B 2 hrs. PHAR 718 3 hrs. PHAR 740 3 hrs. PHAR 742 3 hrs. PHAR 799 6 hrs. STAT 515 3 hrs. STAT 516 3 hrs. Total 35 hrs.   Ph.D. Degree Requirements All students must complete 58 hours of common core courses and 12 hours of courses in one of the following areas of concentration: marketing, policy, or economics. Prerequisite Courses PHRM 547 3 hrs. Required Courses ACCT 728** 3 hrs. ACCT 729** 3 hrs. ECON 621 3 hrs. MKTG 701 3 hrs. MKTG 850 3 hrs. MKTG 853 3 hrs. PHAR 711A—D 4 hrs. PHAR 740 3 hrs. PHAR 741 3 hrs. PHAR 742 3 hrs. PHAR 748 3 hrs. PHAR 899 12 hrs. STAT 515 3 hrs. STAT 516 3 hrs. STAT 518 3 hrs. Area of Concentration* 12 hrs. Total 66—70 hrs. *Three credits from the required courses may be applied if the course is in the student’s chosen area of concentration. **MBAD 728 (5 hrs.) may be substituted for ACCT 728 and ACCT 729. Course Descriptions (PHAR) Medicinal Chemistry 575–Medicinal Chemistry III. {=PHRM 607} (3) (Prereq: fourth college year standing) Clinical applications and chemistry of chemotherapeutic agents. 628–Nutrition in Pharmacy Practice. (3) (Prereq: consent of instructor) Basic concepts of nutrition in health and illness as related to the role of nutrition and nutritional products in therapy. Three lectures per week. 703–Advanced Medicinal Chemistry I. (2) The interaction of natural and synthetic drugs with biological systems at the molecular and quasi-molecular level. 704–Advanced Medicinal Chemistry II. (1—3) (Prereq: PHAR 703) An advanced study of natural and synthetic drugs by pharmacological classes, with emphasis on the application of principles covered in PHAR 703. Lecture and one hour recitation per week. 705–Advanced Medicinal Chemistry III. (2—5) (Prereq: PHAR 703) A continuation of PHAR 704. Lecture and two hours recitation per week. 706–Advanced Medicinal Analysis. (3) A study of the medicinal analyses of an advanced nature with special emphasis on instrumental methods of medicinal analysis. One hour lecture (conf.), six hours laboratory per week. 707–Heterocyclic Medicinal Chemistry. (3) A study of the fundamentals of heterocyclic nomenclature and the chemistry of both the heterocyclic medicinal products and the intermediates for their synthesis. Three hours lecture per week. 708–Natural Products Medicinal Chemistry. (3) The chemistry and biogenesis of alkaloids and antibiotics. Three hours lecture per week. 709–Advanced Biochemistry. (3 or 4) Lectures, seminars, demonstrations and laboratory work on recent and more technical advances in the field of biochemistry. Three lecture and three (optional) laboratory hours per week. 710–Advanced Biochemistry. (3 or 4) Lectures, seminars, demonstrations and laboratory work on recent and more technical advances in the field of biochemistry. Three lecture and three (optional) laboratory hours per week. 713–Synthetic Medicinal Chemistry. (3) Application of synthetic procedures in the preparation of various medicinal and pharmaceutical chemicals and their intermediates. One hour lecture (conf.), six hours laboratory per week. 714–Drug Design by Molecular Modeling and Computational Techniques. (3) (Prereq: consent of instructor) Application of molecular modeling, computer graphics, and other computational techniques to the design of drugs.   Pharmaceutics 501–Cosmetics and Dermatologicals. (3) (Prereq: second professional year standing) Development and manufacture of cosmetics and other dermatological preparations. Two lectures and one laboratory per week. 522–Drug Education. {=PHRM 626, HPRE 540} (3) (Prereq: HPRE 223 or 224 or consent of instructor) Nature of drug actions, motivational factors that influence the use of drugs, and evaluation of procedures to provide effective drug education. 630–Radiopharmaceutics I. (4) (Prereq: consent of instructor) Radiation methodology, safety, and application of radioisotopes in the pharmaceutical and medical sciences. Three lectures and one laboratory per week. 631–Radiopharmaceutics II. (3) (Prereq: PHAR 630) Radiopharmaceutics’ relation to pharmacology, kinetics, biopharmaceutics, and drugs. Clinical indications for selection of drugs and analysis of test results. Two lectures and one laboratory per week. 632–Industrial Pharmaceutical Technology. (4) (Prereq: consent of instructor) Methods and procedures followed in the manufacture, development, and control of pharmaceutical products. Three lectures and one laboratory per week. 646–Intravenous Admixtures. (3) (Prereq: second professional year standing) Parenteral therapy and skills and techniques involved in preparing parenteral admixtures. Two lectures and one laboratory per week. 654–Clinical Pharmacokinetics. (3) Clinical applications of the pharmacokinetic parameter on drug absorption, distribution, biotransformation and excretion as related to dose regimen for therapeutic management of individual patients. Three lectures per week. 701–Dermatological Pharmaceuticals. (3) A study of the formulation, development, manufacture, and control procedures of drug products used as dermatologicals. The course will include: anatomy and physiology of the skin; emollient, cleansing, antiseptic, hormone, photo-protective, photosensitizing, and hypoallergenic ointments, creams, lotions, and sprays; manufacture of selected members of the above group; quality control tests of the manufactured products. Two lecture and three laboratory hours per week. 720–Pharmacokinetics. (3) (Prereq: consent of instructor) A study of the mathematical models used in research to describe drug changes in body fluids as related to pharmacologic effects. Includes the kinetics of dissolution, absorption, distribution, metabolism, and excretion after a drug reaches the general circulation. Three lecture and three laboratory hours per week. 720L–Pharmacokinetics Lab. (1) 725–Advanced Pharmaceutics I. (2) (Prereq: consent of instructor) Physical, chemical, and kinetic concepts which apply to the design and evaluation of pharmaceutical systems. 726–Advanced Pharmaceutics II. (3) (Prereq: PHAR 725 or equivalent course[s]) Application of chemical and physical concepts to the design and evaluation of pharmaceutical systems (dosage forms). Two lectures and one two-hour recitation per week. 732–Radiation Protection. (3) (Prereq: PHAR 630 or consent of instructor) The biological effects of ionizing radiation and the basic mechanisms which bring about these effects. Monitoring, dosimetry, hazard control, and legal responsibilities concerning ionizing radiation used in medicine.   Pharmacology 513–Applied Research in Substance Abuse. {=PHRM 625} (3) (Prereq: consent of instructor) Pharmacological, sociological, psychological, medical, economic, forensic, and other relevant research and treatment disciplines. 564–Pharmacology I. {=PHRM 537} (3) (Prereq: fourth college year standing) Physiological, biochemical, and toxicological actions of drugs in humans and other animals. 565–Pharmacology II. {=PHRM 538} (3) (Prereq: fourth college year standing, PHAR 564) A continuation of PHAR 564. 565L–Pharmacology III Laboratory. (1) (Coreq: PHAR 565) Pharmacological principles and agents in animals. 566–Toxicology. (3) (Coreq: PHAR 565) Advanced concepts and mechanisms of toxicity of chemicals of environmental, commercial, pharmaceutical and household agents. 727–An Introduction to Pharmacological Methods in Research. {=PCOL 727} (2) Emphasis is placed on the theoretical and practical knowledge necessary to conduct research in biochemical-, physiological-, and neuro-pharmacology and toxicology. Both in vivo and in vitro techniques will be used. One lecture and three laboratory hours per week. 734–Selected Topics in Neuropharmacology. (2) (Prereq: PHAR 736) Neurochemical analysis of selected central nervous system neurotransmitter topics, including the kinetics of synthesis, storage and release, and the action of selected psychotherapeutic agents on these processes. 735–Cancer Biochemistry and Pharmacology. (2) (Prereq: permission of instructor) The molecular and biochemical basis of cancer and the therapeutic approaches in the prevention and treatment of cancer. 736–Advanced Pharmacology I. (1 or 4) (Prereq: PHAR 738 or permission of instructor) Survey of drugs acting on the autonomic nervous system and the cardiovascular system; advanced topics in these areas and on antibiotics and chemotherapy. Three lectures and one two-hour recitation session per week. 737–Advanced Pharmacology II. (1 or 4) (Prereq: PHAR 738 or permission of instructor) Survey of centrally acting drugs, anti-inflammatory and immunomodulating drugs, hormones, and vitamins; advanced topics in these areas and in drug design and drug toxicity/teratogenesis. Three lectures and one two-hour recitation session per week. 738–Basic Pharmacological Principles. (2) (Prereq: consent of instructor) Factors that govern drug response, biochemical and molecular actions of drugs, and adverse effects induced by drugs.   Pharmaceutical and Health Outcome Sciences 557–Institutional Pharmacy Practice and Operations. (3) (Prereq: PHRM 645) Delivery of pharmaceutical services to institutionalized patients; institutional pharmacy operations and management; pertinent laws and regulations. Two lectures and one two-hour recitation per week. 559–Community Pharmacy Practice and Operations. (3) (Prereq: PHRM 645) Management and operations of a community pharmacy practice, managerial accounting concepts, pertinent laws and regulations. Two lectures and one two-hour recitation per week. 711A–Seminar in Pharmacy Administration. (1 each) Discussion and presentation of current topics in pharmacy administration. Required of all master’s degree (2 credit hours) and Ph.D. degree (3 credit hours) candidates in the Department of Pharmacy Practice. 711B–Seminar in Pharmacy Administration. (1 each) Discussion and presentation of current topics in pharmacy administration. Required of all master’s degree (2 credit hours) and Ph.D. degree (3 credit hours) candidates in the Department of Pharmacy Practice. 711C–Seminar in Pharmacy Administration. (1 each) Discussion and presentation of current topics in pharmacy administration. Required of all master’s degree (2 credit hours) and Ph.D. degree (3 credit hours) candidates in the Department of Pharmacy Practice. 711D–Seminar in Pharmacy Administration. (1 each) Discussion and presentation of current topics in pharmacy administration. Required of all master’s degree (2 credit hours) and Ph.D. degree (3 credit hours) candidates in the Department of Pharmacy Practice. 740–Socio-Economics of Pharmacy Practice. (3) An analysis of practice environments of pharmacists. Emphasis on the drug using public and health care providers in terms of economics, social, and health factors. Detailed analysis of the third-party prescription market including prescribing behavior, drug use, cost containment, legal issues, and quality of care. 741–Pharmaceutical Outcomes Database Development. (3) Development and use of pharmaceutical outcomes databases. 742–Research Methods in Pharmacy Administration. (3) (Prereq: STAT 516 or consent of instructor) The nature of the research process in the administrative and behavioral aspects of pharmacy practice. Emphasis on developing the skills to analyze the total drug use process. 744–Marketing of Drug Products. (3) (Prereq: BADM 751–Marketing Management) The principles of marketing as applied to pharmaceutical products. Topics include various marketing institutions and the integration of these into the drug distribution system, and the duties of the market manager in a pharmaceutical firm. 745–International Pharmaceutical Marketing. (3) The principles of marketing applied to the international pharmaceutical industry. Emphasis on the marketing environment and institutions of pharmaceutical marketing in global markets. 746–Drug Benefits in Health Care Programs. (3) (Prereq: graduate standing) Detailed analysis of the third party prescription market including prescribing behavior, drug use, cost containment, legal issues, and quality of care. 748–Principles of Pharmacoeconomics. (3) (Prereq: ECON 727, ACCT 729) Analytical techniques and theoretical principles for evaluating costs and consequences of pharmaceutical agents and services for the health care system and society.   Pharmaceutical Sciences 527–Problems in Pharmacy I. (1—6 credits, content and credits to be arranged) Conferences, assignments, and laboratory. Elective course. Contract approved by instructor, advisor, and department head is required for undergraduate students. 528–Problems in Pharmacy II. (1—6 credits, content and credits to be arranged) Conferences, assignments, and laboratory. Elective course. Contract approved by instructor, advisor, and department head is required for undergraduate students. 712A–Seminar in Pharmaceutical Sciences. (1 each) Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of four credit hours may be earned in PHAR 712 A—D. 712B–Seminar in Pharmaceutical Sciences. (1 each) Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of four credit hours may be earned in PHAR 712 A—D. 712C–Seminar in Pharmaceutical Sciences. (1 each) Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of four credit hours may be earned in PHAR 712 A—D. 712D–Seminar in Pharmaceutical Sciences. (1 each) Discussion of current topics in pharmaceutics, medicinal chemistry, and pharmacology. Required of all students. A maximum of four credit hours may be earned in PHAR 712 A—D. 717–Special Topics in Pharmacy. (3) Lectures, readings, and discussions on special areas of experimental pharmacy not offered in other courses. Three lectures per week. 718–Special Topics in Pharmacy. (3) Lectures, readings, and discussions on special areas of experimental pharmacy not offered in other courses. Three lectures per week. 799–Thesis Preparation. (1—6) 899–Dissertation Preparation. (1—12) [Bulletin Home Page] [Graduate Bulletin Contents] [Disclaimer] [The Graduate School] This web site updated September 2001 by Thom Harman, and copyright © 2001-2002 by the Board of Trustees of the University of South Carolina. All Rights Reserved. URL http://www.sc.edu/bulletin/grad/GColPharm.html